AutismKB 2.0

Annotation Details for ARAF


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Basic Information Top
Gene Symbol:ARAF ( A-RAF,ARAF1,PKS2,RAFA1 )
Gene Full Name: v-raf murine sarcoma 3611 viral oncogene homolog
Band: Xp11.3
Quick LinksEntrez ID:369; OMIM: 311010; Uniprot ID:ARAF_HUMAN; ENSEMBL ID: ENSG00000078061; HGNC ID: 646
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005739IBA-mitochondrion-
GO:0005829IBA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004672TAS-protein kinase activity3029685
GO:0004674IDA-protein serine/threonine kinase activity19667065
GO:0004709IBA-MAP kinase kinase kinase activity-
GO:0005515IPI-protein binding11909642
GO:0005524IEA-ATP binding-
GO:0031434IBA-mitogen-activated protein kinase kinase binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000186IEA-activation of MAPKK activity-
GO:0006464TAS-cellular protein modification process3029685
GO:0007275IBA-multicellular organism development-
GO:0009968IBA-negative regulation of signal transduction-
GO:0030154IBA-cell differentiation-
GO:0032006IMP-regulation of TOR signaling22609986
GO:0032434IMP-regulation of proteasomal ubiquitin-dependent protein catabolic process22609986
GO:0033138IDA-positive regulation of peptidyl-serine phosphorylation19667065
GO:0043066IDA-negative regulation of apoptotic process19667065
GO:0070374IBA-positive regulation of ERK1 and ERK2 cascade-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CSNK2BARAF1078439042965 Two-hybrid
CSNK2BARAF1068649042965 Two-hybrid
TIMM44ARAF11573210848612 12620389 Two-hybrid
TIMM44ARAF10686410848612 12620389 Two-hybrid
PRPF6ARAF11729810848612 12620389 Two-hybrid
PRPF6ARAF10686410848612 12620389 Two-hybrid
RRASARAF11215110848612 12620389 Two-hybrid
RRASARAF10686410848612 12620389 Two-hybrid
PIK3R1ARAF11131311812000 Reconstituted Complex
PIK3R1ARAF10686411812000 Reconstituted Complex
MAP2K2ARAF11159111909642 Reconstituted Complex; Two-hybrid
MAP2K2ARAF10686411909642 Reconstituted Complex; Two-hybrid
TH1LARAF11957211952167 12620389 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TH1LARAF10686411952167 12620389 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAHARAF11336511969417 Affinity Capture-Western
YWHAHARAF10686411969417 Affinity Capture-Western
EFEMP1ARAF10849612620389 Two-hybrid
EFEMP1ARAF10686412620389 Two-hybrid
ASS1ARAF10693712620389 Two-hybrid
ASS1ARAF10686412620389 Two-hybrid
PBKARAF12097112620389 Two-hybrid
PBKARAF10686412620389 Two-hybrid
RABGGTBARAF11181412620389 Two-hybrid
RABGGTBARAF10686412620389 Two-hybrid
COPS3ARAF11410312620389 Two-hybrid
COPS3ARAF10686412620389 Two-hybrid
SFNARAF10907215778465 Affinity Capture-MS
SFNARAF10686415778465 Affinity Capture-MS
KLHL12ARAF12189016189514 Two-hybrid
KLHL12ARAF10686416189514 Two-hybrid
YWHAGARAF11336417353931 Affinity Capture-MS
YWHAGARAF10686417353931 Affinity Capture-MS
MYO18AARAF13438420936779 Two-hybrid
MYO18AARAF10686420936779 Two-hybrid
YWHAEARAF11336320936779 Two-hybrid
YWHAEARAF10686420936779 Two-hybrid
YWHAZARAF11336620936779 Two-hybrid
YWHAZARAF10686420936779 Two-hybrid
CHD6ARAF10686420936779 Two-hybrid
CHD6ARAF12393120936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88065
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050102-2'