AutismKB 2.0

Annotation Details for JAG2


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Basic Information Top
Gene Symbol:JAG2 ( HJ2,SER2 )
Gene Full Name: jagged 2
Band: 14q32.33
Quick LinksEntrez ID:3714; OMIM: 602570; Uniprot ID:JAG2_HUMAN; ENSEMBL ID: ENSG00000184916; HGNC ID: 6189
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane10910909
GO ID Evidence Qualifier GO_term References
GO:0005112IPI-Notch binding9315665
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding16713569
GO:0008083IDA-growth factor activity10383933
GO ID Evidence Qualifier GO_term References
GO:0001501IEA-skeletal system development-
GO:0001701IEA-in utero embryonic development-
GO:0003016IEA-respiratory system process-
GO:0007049NAS-cell cycle11549580
GO:0007219NAS-Notch signaling pathway11056013
GO:0007219TAS-Notch signaling pathway-
GO:0007220TAS-Notch receptor processing-
GO:0007283IEP-spermatogenesis11700865
GO:0009912ISS-auditory receptor cell fate commitment10080181
GO:0016331IEA-morphogenesis of embryonic epithelium-
GO:0030154IDA-cell differentiation11549580
GO:0030155IEA-regulation of cell adhesion-
GO:0030217IDA-T cell differentiation10383933
GO:0030334NAS-regulation of cell migration11549580
GO:0042127IDA-regulation of cell proliferation10383933
GO:0042475IEA-odontogenesis of dentin-containing tooth-
GO:0042492IEA-gamma-delta T cell differentiation-
GO:0045061IDA-thymic T cell selection10383933
GO:0045747ISS-positive regulation of Notch signaling pathway-
GO:1990134IEA-epithelial cell apoptotic process involved in palatal shelf morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NOTCH2JAG211091510958687 Affinity Capture-Western; Reconstituted Complex
NOTCH2JAG210991810958687 Affinity Capture-Western; Reconstituted Complex
NOTCH1JAG211091311006133 Reconstituted Complex
NOTCH1JAG210991811006133 Reconstituted Complex
NOTCH3JAG211091611006133 Reconstituted Complex
NOTCH3JAG210991811006133 Reconstituted Complex
MIB2JAG212676915920166 Reconstituted Complex
MIB2JAG210991815920166 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
JAG2rs1057744 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1098270
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-011128-3'