AutismKB 2.0

Annotation Details for AGRN


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Basic Information Top
Gene Symbol:AGRN ( FLJ45064 )
Gene Full Name: agrin
Band: 1p36.33
Quick LinksEntrez ID:375790; OMIM: 103320; Uniprot ID:AGRIN_HUMAN; ENSEMBL ID: ENSG00000188157; HGNC ID: 329
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005605IDA-basal lamina9405491
GO:0005796TAS-Golgi lumen-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0030054IEA-cell junction-
GO:0031012IDA-extracellular matrix17628813
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0031012TAScolocalizes_withextracellular matrix22261194
GO:0043202TAS-lysosomal lumen-
GO:0045202ISS-synapse-
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0002162ISS-dystroglycan binding-
GO:0005200TAS-structural constituent of cytoskeleton9652404
GO:0005509ISS-calcium ion binding-
GO:0005515IPI-protein binding9417121
GO:0033691ISS-sialic acid binding-
GO:0035374ISS-chondroitin sulfate binding-
GO:0043236TAS-laminin binding9652404
GO:0043395ISS-heparan sulfate proteoglycan binding-
GO ID Evidence Qualifier GO_term References
GO:0001523TAS-retinoid metabolic process-
GO:0006024TAS-glycosaminoglycan biosynthetic process-
GO:0006027TAS-glycosaminoglycan catabolic process-
GO:0007010IEA-cytoskeleton organization-
GO:0007165TAS-signal transduction9652404
GO:0007213TAS-G-protein coupled acetylcholine receptor signaling pathway9405491
GO:0030198TAS-extracellular matrix organization-
GO:0030203TAS-glycosaminoglycan metabolic process-
GO:0043113IDA-receptor clustering15340048
GO:0043113IMP-receptor clustering9151673
GO:0043547ISS-positive regulation of GTPase activity-
GO:0045162TAS-clustering of voltage-gated sodium channels9405491
GO:0045887ISS-positive regulation of synaptic growth at neuromuscular junction-
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0050808TAS-synapse organization9652404
GO:0051491ISS-positive regulation of filopodium assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AGRNDAG11320008205617 Far Western
AGRNDAG11079758205617 Far Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:87961
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1033'