Gene Symbol:	USP17L2 ( DUB3 )
Gene Full Name:	ubiquitin specific peptidase 17-like 2
Band:	8p23.1
Quick Links	Entrez ID:377630; OMIM: 610186; Uniprot ID:U17L2_HUMAN; ENSEMBL ID: ENSG00000223443; HGNC ID: 34434
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IDA	-	nucleus	21239494
GO:0005789	IDA	-	endoplasmic reticulum membrane	19188362
GO:0005829	TAS	-	cytosol	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004843	IDA	-	thiol-dependent ubiquitin-specific protease activity	20228808
GO:0004843	IMP	-	thiol-dependent ubiquitin-specific protease activity	19188362
GO:0005515	IPI	-	protein binding	21239494
GO:0036459	TAS	-	thiol-dependent ubiquitinyl hydrolase activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000075	IMP	-	cell cycle checkpoint	20228808
GO:0006511	IEA	-	ubiquitin-dependent protein catabolic process	-
GO:0006915	IEA	-	apoptotic process	-
GO:0007093	IMP	-	mitotic cell cycle checkpoint	20228808
GO:0010955	IMP	-	negative regulation of protein processing	19188362
GO:0016579	IDA	-	protein deubiquitination	20228808
GO:0016579	TAS	-	protein deubiquitination	-
GO:0030334	IMP	-	regulation of cell migration	21448158
GO:0031064	IMP	-	negative regulation of histone deacetylation	21239494
GO:0034260	IDA	-	negative regulation of GTPase activity	19188362
GO:0042127	IMP	-	regulation of cell proliferation	19188362
GO:0042981	IMP	-	regulation of apoptotic process	21239494
GO:0043547	IMP	-	positive regulation of GTPase activity	21448158
GO:0050691	IMP	-	regulation of defense response to virus by host	20368735
GO:0070536	IDA	-	protein K63-linked deubiquitination	21239494
GO:0070536	IMP	-	protein K63-linked deubiquitination	19188362
GO:0071108	IMP	-	protein K48-linked deubiquitination	19188362
GO:0071586	IMP	-	CAAX-box protein processing	19188362
GO:0090315	IMP	-	negative regulation of protein targeting to membrane	19188362
GO:1900027	IMP	-	regulation of ruffle assembly	21448158
GO:1900245	IMP	-	positive regulation of MDA-5 signaling pathway	20368735
GO:1900246	IMP	-	positive regulation of RIG-I signaling pathway	20368735

Gene Symbol	Interactant	Interaction ID	References	Description
USP17L2	SET	132019	19615732	Affinity Capture-MS
USP17L2	SET	112316	19615732	Affinity Capture-MS
USP17L2	CBX1	132019	19615732	Affinity Capture-MS
USP17L2	CBX1	116151	19615732	Affinity Capture-MS
USP17	USP17L2	133990	19615732	Affinity Capture-MS
USP17	USP17L2	132019	19615732	Affinity Capture-MS
USP17L7	USP17L2	134130	19615732	Affinity Capture-MS
USP17L7	USP17L2	132019	19615732	Affinity Capture-MS

AutismKB 2.0

Annotation Details for USP17L2