AutismKB 2.0

Annotation Details for KCNN2


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Basic Information Top
Gene Symbol:KCNN2 ( KCa2.2,SK2,SKCA2,hSK2 )
Gene Full Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Band: 5q22.3
Quick LinksEntrez ID:3781; OMIM: 605879; Uniprot ID:KCNN2_HUMAN; ENSEMBL ID: ENSG00000080709; HGNC ID: 6291
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane19815520
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface19815520
GO:0016021NAS-integral component of membrane10991935
GO:0030018ISS-Z disc24951510
GO:0043025IBA-neuronal cell body-
GO:0043197IBA-dendritic spine-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding24951510
GO:0005516IBA-calmodulin binding-
GO:0015269IDA-calcium-activated potassium channel activity17110593
GO:0016286IDA-small conductance calcium-activated potassium channel activity24951510
GO:0016286IMP-small conductance calcium-activated potassium channel activity19815520
GO:0016286ISS-small conductance calcium-activated potassium channel activity19139040
GO:0016286TAS-small conductance calcium-activated potassium channel activity10991935
GO:0019904IPI-protein domain specific binding19815520
GO:0042803IPI-protein homodimerization activity17110593
GO:0051393IPI-alpha-actinin binding17110593
GO ID Evidence Qualifier GO_term References
GO:0006813NAS-potassium ion transport10991935
GO:0071805IDA-potassium ion transmembrane transport17110593
GO:0071805ISS-potassium ion transmembrane transport19139040
GO:0098914ISS-membrane repolarization during atrial cardiac muscle cell action potential19139040
GO:1901379IDA-regulation of potassium ion transmembrane transport17110593
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KCNN2CALM110998211323678 Co-crystal Structure
KCNN2CALM110725211323678 Co-crystal Structure
KCNN2KCNN210998211323678 Co-crystal Structure
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2153182
  • Data Attributes: MGI curated and HomoloGene calculated
No data