AutismKB 2.0

Annotation Details for KIF5B


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Basic Information Top
Gene Symbol:KIF5B ( KINH,KNS,KNS1,UKHC )
Gene Full Name: kinesin family member 5B
Band: 10p11.22
Quick LinksEntrez ID:3799; OMIM: 602809; Uniprot ID:KINH_HUMAN; ENSEMBL ID: ENSG00000170759; HGNC ID: 6324
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005815IDA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005871TAS-kinesin complex1607388
GO:0005874IEA-microtubule-
GO:0016020IDA-membrane19946888
GO:0030139IEA-endocytic vesicle-
GO:0031982IDA-vesicle20682791
GO:0035253IEA-ciliary rootlet-
GO:0044295IEA-axonal growth cone-
GO:0048471ISS-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003777ISS-microtubule motor activity-
GO:0005515IPI-protein binding19164528
GO:0005524IEA-ATP binding-
GO:0008017ISS-microtubule binding-
GO:0008432IEA-JUN kinase binding-
GO:0008574IBA-ATP-dependent microtubule motor activity, plus-end-directed-
GO:0045296IDA-cadherin binding25468996
GO:0099609IEA-microtubule lateral binding-
GO ID Evidence Qualifier GO_term References
GO:0007018TAS-microtubule-based movement7514426
GO:0007028IEA-cytoplasm organization-
GO:0007411IBA-axon guidance-
GO:0021766IEA-hippocampus development-
GO:0030705IBA-cytoskeleton-dependent intracellular transport-
GO:0031340IEA-positive regulation of vesicle fusion-
GO:0032230IEA-positive regulation of synaptic transmission, GABAergic-
GO:0035617ISS-stress granule disassembly-
GO:0035774IEA-positive regulation of insulin secretion involved in cellular response to glucose stimulus-
GO:0042391IDA-regulation of membrane potential19675065
GO:0043268IDA-positive regulation of potassium ion transport19675065
GO:0047496ISS-vesicle transport along microtubule-
GO:0051642IMP-centrosome localization20386726
GO:0072383IEA-plus-end-directed vesicle transport along microtubule-
GO:0090004IDA-positive regulation of establishment of protein localization to plasma membrane19675065
GO:0090316IEA-positive regulation of intracellular protein transport-
GO:1905152IEA-positive regulation of voltage-gated sodium channel activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KIF5BAPC10682120936779 Two-hybrid
KIF5BAPC11000020936779 Two-hybrid
KIF5BDTNB10817114600269 Reconstituted Complex
KIF5BDTNB11000014600269 Reconstituted Complex
KIF5BMARK210832619615732 Affinity Capture-MS
KIF5BMARK211000019615732 Affinity Capture-MS
KIF5BSFN10907215778465 Affinity Capture-MS
KIF5BSFN11000015778465 Affinity Capture-MS
KIF5CKIF5B1100019624122 Affinity Capture-Western
KIF5CKIF5B1100009624122 Affinity Capture-Western
KLC2KIF5B1223139624122 10491391 Affinity Capture-Western
KLC2KIF5B1100009624122 10491391 Affinity Capture-Western
KLC1KIF5B1100299624122 10491391 12475239 Affinity Capture-Western; Reconstituted Complex
KLC1KIF5B1100009624122 10491391 12475239 Affinity Capture-Western; Reconstituted Complex
YWHAHKIF5B11000011969417 Affinity Capture-MS; Far Western
YWHAHKIF5B11336511969417 Affinity Capture-MS; Far Western
SNAP25KIF5B11250012475239 Reconstituted Complex; Two-hybrid
SNAP25KIF5B11000012475239 Reconstituted Complex; Two-hybrid
SNAP23KIF5B11430312475239 Reconstituted Complex; Two-hybrid
SNAP23KIF5B11000012475239 Reconstituted Complex; Two-hybrid
YWHAQKIF5B11616817353931 Affinity Capture-MS
YWHAQKIF5B11000017353931 Affinity Capture-MS
NME2KIF5B11089517353931 Affinity Capture-MS
NME2KIF5B11000017353931 Affinity Capture-MS
VDAC1KIF5B11000017353931 Affinity Capture-MS
VDAC1KIF5B11325917353931 Affinity Capture-MS
YWHABKIF5B11000017353931 Affinity Capture-MS
YWHABKIF5B11336117353931 Affinity Capture-MS
YWHAGKIF5B11336417353931 Affinity Capture-MS
YWHAGKIF5B11000017353931 Affinity Capture-MS
YWHAZKIF5B11000017353931 Affinity Capture-MS
YWHAZKIF5B11336617353931 Affinity Capture-MS
MEPCEKIF5B12112217643375 Affinity Capture-MS
MEPCEKIF5B11000017643375 Affinity Capture-MS
USPL1KIF5B11000019615732 Affinity Capture-MS
USPL1KIF5B11550319615732 Affinity Capture-MS
FYCO1KIF5B12266920562859 Affinity Capture-MS
FYCO1KIF5B11000020562859 Affinity Capture-MS
RAPGEF2KIF5B11000020936779 Two-hybrid
RAPGEF2KIF5B11504520936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1098268
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070629-2'