AutismKB 2.0

Annotation Details for ARG1


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Basic Information Top
Gene Symbol:ARG1 ( - )
Gene Full Name: arginase, liver
Band: 6q23.2
Quick LinksEntrez ID:383; OMIM: 608313; Uniprot ID:ARGI1_HUMAN; ENSEMBL ID: ENSG00000118520; HGNC ID: 663
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005634IDA-nucleus21630459
GO:0005737TAS-cytoplasm3540966
GO:0005741IEA-mitochondrial outer membrane-
GO:0005829TAS-cytosol-
GO:0035578TAS-azurophil granule lumen-
GO:0035580TAS-specific granule lumen-
GO:0043005IEA-neuron projection-
GO:0043025IEA-neuronal cell body-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004053EXP-arginase activity16141327
GO:0030145IEA-manganese ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000050IEA-urea cycle-
GO:0000050TAS-urea cycle-
GO:0001889IEA-liver development-
GO:0001938IEA-positive regulation of endothelial cell proliferation-
GO:0006527TAS-arginine catabolic process3540966
GO:0007568IEA-aging-
GO:0009635IEA-response to herbicide-
GO:0010042IEA-response to manganese ion-
GO:0010043IEA-response to zinc ion-
GO:0010269IEA-response to selenium ion-
GO:0010963IEA-regulation of L-arginine import-
GO:0014075IEA-response to amine-
GO:0019547IEA-arginine catabolic process to ornithine-
GO:0030324IEA-lung development-
GO:0032964IEA-collagen biosynthetic process-
GO:0033189IEA-response to vitamin A-
GO:0033197IEA-response to vitamin E-
GO:0042493IEA-response to drug-
GO:0043200IEA-response to amino acid-
GO:0043312TAS-neutrophil degranulation-
GO:0046686IEA-response to cadmium ion-
GO:0048678IEA-response to axon injury-
GO:0051597IEA-response to methylmercury-
GO:0060056IEA-mammary gland involution-
GO:0060135IEA-maternal process involved in female pregnancy-
GO:0070207IEA-protein homotrimerization-
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071353IEA-cellular response to interleukin-4-
GO:0071377IEA-cellular response to glucagon stimulus-
GO:0071549IEA-cellular response to dexamethasone stimulus-
GO:0071560IEA-cellular response to transforming growth factor beta stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
USP53ARG112002019615732 Affinity Capture-MS
USP53ARG110687819615732 Affinity Capture-MS
C12orf44ARG112194820562859 Affinity Capture-MS
C12orf44ARG110687820562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88070
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018