Gene Symbol:	KRT1 ( CK1,EHK,EHK1,EPPK,K1,KRT1A,NEPPK )
Gene Full Name:	keratin 1
Band:	12q13.13
Quick Links	Entrez ID:3848; OMIM: 139350; Uniprot ID:K2C1_HUMAN; ENSEMBL ID: ENSG00000167768; HGNC ID: 6412
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0001533	IDA	-	cornified envelope	7543090
GO:0005576	TAS	-	extracellular region	-
GO:0005615	IDA	-	extracellular space	22664934
GO:0005634	IDA	-	nucleus	21630459
GO:0005829	TAS	-	cytosol	-
GO:0005856	TAS	-	cytoskeleton	1381288
GO:0016020	IDA	-	membrane	11290596
GO:0031012	IDA	-	extracellular matrix	23658023
GO:0045095	IEA	-	keratin filament	-
GO:0070062	IDA	-	extracellular exosome	11487543
GO:0072562	IDA	-	blood microparticle	22516433
GO:1904813	TAS	-	ficolin-1-rich granule lumen	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004872	NAS	-	receptor activity	11290596
GO:0005515	IPI	-	protein binding	11290596
GO:0030246	IPI	-	carbohydrate binding	11549596
GO:0030280	IDA	-	structural constituent of epidermis	7543090

GO ID	Evidence	Qualifier	GO_term	References
GO:0001867	IPI	-	complement activation, lectin pathway	11549596
GO:0001895	IEP	-	retina homeostasis	23580065
GO:0006979	NAS	-	response to oxidative stress	11549596
GO:0018149	IDA	-	peptide cross-linking	7543090
GO:0031424	TAS	-	keratinization	-
GO:0042730	NAS	-	fibrinolysis	11290596
GO:0043312	TAS	-	neutrophil degranulation	-
GO:0045765	NAS	-	regulation of angiogenesis	11290596
GO:0050728	IEA	-	negative regulation of inflammatory response	-
GO:0061436	IEA	-	establishment of skin barrier	-
GO:0070268	TAS	-	cornification	-
GO:0098773	IC	-	skin epidermis development	7543090

Gene Symbol	Interactant	Interaction ID	References	Description
KRT1	CSTA	110046	8999895	Reconstituted Complex
KRT1	CSTA	107857	8999895	Reconstituted Complex
KRT1	DSP	108166	9261168	Reconstituted Complex; Two-hybrid
KRT1	DSP	110046	9261168	Reconstituted Complex; Two-hybrid
KRT1	FANCA	108472	14499622	Two-hybrid
KRT1	FANCA	110046	14499622	Two-hybrid
KRT1	FANCC	110046	14499622	Two-hybrid
KRT1	FANCC	108473	14499622	Two-hybrid
KRT1	IVL	109917	8999895	Reconstituted Complex
KRT1	IVL	110046	8999895	Reconstituted Complex
KRT1	KNG1	110026	10066772	Reconstituted Complex
KRT1	KNG1	110046	10066772	Reconstituted Complex
LOR	KRT1	110198	8999895	Reconstituted Complex
LOR	KRT1	110046	8999895	Reconstituted Complex
PI3	KRT1	110046	8999895	Reconstituted Complex
PI3	KRT1	111284	8999895	Reconstituted Complex
MBL2	KRT1	110323	11549596	Affinity Capture-Western
MBL2	KRT1	110046	11549596	Affinity Capture-Western
PRKCE	KRT1	110046	11897493	Affinity Capture-MS; Affinity Capture-Western
PRKCE	KRT1	111567	11897493	Affinity Capture-MS; Affinity Capture-Western

AutismKB 2.0

Annotation Details for KRT1