AutismKB 2.0

Annotation Details for KRT16


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Basic Information Top
Gene Symbol:KRT16 ( CK16,FNEPPK,K16,K1CP,KRT16A,NEPPK )
Gene Full Name: keratin 16
Band: 17q21.2
Quick LinksEntrez ID:3868; OMIM: 148067; Uniprot ID:K1C16_HUMAN; ENSEMBL ID: ENSG00000186832; HGNC ID: 6423
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21630459
GO:0005829TAS-cytosol-
GO:0005856IDA-cytoskeleton20403371
GO:0005882NAS-intermediate filament2451124
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0005200NAS-structural constituent of cytoskeleton2451124
GO:0005515IPI-protein binding15731013
GO ID Evidence Qualifier GO_term References
GO:0002009ISS-morphogenesis of an epithelium-
GO:0006954ISS-inflammatory response-
GO:0007010NAS-cytoskeleton organization2451124
GO:0007568IDA-aging21916889
GO:0008283TAS-cell proliferation8595410
GO:0008544TAS-epidermis development7539673
GO:0030216ISS-keratinocyte differentiation-
GO:0030336IDA-negative regulation of cell migration20403371
GO:0031424ISS-keratinization-
GO:0031424TAS-keratinization-
GO:0042633IDA-hair cycle21916889
GO:0045087ISS-innate immune response-
GO:0045104IEA-intermediate filament cytoskeleton organization-
GO:0051546ISS-keratinocyte migration-
GO:0061436ISS-establishment of skin barrier-
GO:0070268TAS-cornification-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BANF1KRT1611006619759913 Affinity Capture-MS
BANF1KRT1611434219759913 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96690
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018