AutismKB 2.0

Annotation Details for KRT18


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Basic Information Top
Gene Symbol:KRT18 ( CYK18,K18 )
Gene Full Name: keratin 18
Band: 12q13.13
Quick LinksEntrez ID:3875; OMIM: 148070; Uniprot ID:K1C18_HUMAN; ENSEMBL ID: ENSG00000111057; HGNC ID: 6430
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005730IEA-nucleolus-
GO:0005737IDA-cytoplasm16424149
GO:0005815IDA-microtubule organizing center18000879
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005882IDA-intermediate filament10852826
GO:0005913IDA-cell-cell adherens junction25468996
GO:0034451IDA-centriolar satellite18000879
GO:0045095IDA-keratin filament16424149
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome19199708
GO:0071944IEA-cell periphery-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005198IEA-structural molecule activity-
GO:0005515IPI-protein binding10852826
GO:0097110IPI-scaffold protein binding10852826
GO:0098641IDA-cadherin binding involved in cell-cell adhesion25468996
GO ID Evidence Qualifier GO_term References
GO:0007049IEA-cell cycle-
GO:0009653TAS-anatomical structure morphogenesis2434380
GO:0016032IEA-viral process-
GO:0031424TAS-keratinization-
GO:0033209IEA-tumor necrosis factor-mediated signaling pathway-
GO:0043000IDA-Golgi to plasma membrane CFTR protein transport15529338
GO:0043066IDA-negative regulation of apoptotic process11684708
GO:0045104IDA-intermediate filament cytoskeleton organization20346438
GO:0070268TAS-cornification-
GO:0097191IEA-extrinsic apoptotic signaling pathway-
GO:0097284IEA-hepatocyte apoptotic process-
GO:0098609IEA-cell-cell adhesion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KRT18ALK10673914968112 Affinity Capture-MS
KRT18ALK11007314968112 Affinity Capture-MS
KRT18CBL1073159367879 Two-hybrid
KRT18CBL1100739367879 Two-hybrid
KRT18COL17A110770410022517 Reconstituted Complex; Two-hybrid
KRT18COL17A111007310022517 Reconstituted Complex; Two-hybrid
KRT18GRB210914212577067 Affinity Capture-MS
KRT18GRB211007312577067 Affinity Capture-MS
KRT18HSPA41100737529764 Reconstituted Complex
KRT18HSPA41095407529764 Reconstituted Complex
KRT18KRT51100509786957 Co-purification
KRT18KRT51100739786957 Co-purification
KRT18KRT81100549630597 Two-hybrid
KRT18KRT81100739630597 Two-hybrid
KRT18KRT1511006416189514 Two-hybrid
KRT18KRT1511007316189514 Two-hybrid
PRKCEKRT181100731374067 Affinity Capture-Western
PRKCEKRT181115671374067 Affinity Capture-Western
YWHAQKRT181100739524113 Affinity Capture-Western
YWHAQKRT181161689524113 Affinity Capture-Western
KRT72KRT181100739630597 Two-hybrid
KRT72KRT181267159630597 Two-hybrid
TNFRSF1BKRT1811007310747083 Reconstituted Complex
TNFRSF1BKRT1811298710747083 Reconstituted Complex
PNNKRT1811007310809736 Reconstituted Complex; Two-hybrid
PNNKRT1811141210809736 Reconstituted Complex; Two-hybrid
PKP2KRT1811007310852826 Reconstituted Complex
PKP2KRT1811133510852826 Reconstituted Complex
DNAJB6KRT1811007310954706 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DNAJB6KRT1811536010954706 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PKD1KRT1811007311581269 Reconstituted Complex
PKD1KRT1811132711581269 Reconstituted Complex
TRADDKRT1811007311684708 Affinity Capture-Western; Two-hybrid
TRADDKRT1811425711684708 Affinity Capture-Western; Two-hybrid
DEDDKRT1811007312235123 Affinity Capture-Western
DEDDKRT1811462712235123 Affinity Capture-Western
PKP3KRT1811635712707304 Two-hybrid
PKP3KRT1811007312707304 Two-hybrid
CCDC85BKRT1811007316189514 Two-hybrid
CCDC85BKRT1811619816189514 Two-hybrid
EXOC8KRT1811007316189514 Two-hybrid
EXOC8KRT1812720616189514 Two-hybrid
LDOC1KRT1811716916189514 Two-hybrid
LDOC1KRT1811007316189514 Two-hybrid
TUBGCP4KRT1811007316189514 Two-hybrid
TUBGCP4KRT1811807816189514 Two-hybrid
NME7KRT1811007316189514 Two-hybrid
NME7KRT1811896316189514 Two-hybrid
HGSKRT1811007316189514 Two-hybrid
HGSKRT1811459316189514 Two-hybrid
MCCKRT1811007317353931 Affinity Capture-MS
MCCKRT1811033317353931 Affinity Capture-MS
PPM1BKRT1811149017353931 Affinity Capture-MS
PPM1BKRT1811007317353931 Affinity Capture-MS
CLEC3BKRT1811007317353931 Affinity Capture-MS
CLEC3BKRT1811297817353931 Affinity Capture-MS
USP32KRT1811007319615732 Affinity Capture-MS
USP32KRT1812418919615732 Affinity Capture-MS
YWHAGKRT1811007320936779 Two-hybrid
YWHAGKRT1811336420936779 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
PKP3KRT1825967212707304 PKP3 interacts with KRT18 (CK18)
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96692
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030411-6'