Annotation Details for RHOB
Basic Information Top
| Gene Symbol: | RHOB ( ARH6,ARHB,MST081,MSTP081,RHOH6 ) |
|---|---|
| Gene Full Name: | ras homolog gene family, member B |
| Band: | 2p24.1 |
| Quick Links | Entrez ID:388; OMIM: 165370; Uniprot ID:RHOB_HUMAN; ENSEMBL ID: ENSG00000143878; HGNC ID: 668 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005634 | ISS | - | nucleus | - |
| GO:0005769 | IEA | - | early endosome | - |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0005886 | IDA | - | plasma membrane | 15226397 |
| GO:0005886 | TAS | - | plasma membrane | - |
| GO:0005925 | IDA | - | focal adhesion | 21423176 |
| GO:0010008 | IDA | - | endosome membrane | 15226397 |
| GO:0010008 | TAS | - | endosome membrane | - |
| GO:0031902 | IEA | - | late endosome membrane | - |
| GO:0032154 | IDA | - | cleavage furrow | 16236794 |
| GO:0070062 | IDA | - | extracellular exosome | 19056867 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003924 | TAS | - | GTPase activity | 3888408 |
| GO:0005515 | IPI | - | protein binding | 19637314 |
| GO:0005525 | TAS | - | GTP binding | 1400319 |
| GO:0019003 | IEA | - | GDP binding | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000910 | IMP | - | cytokinesis | 16236794 |
| GO:0001525 | IEA | - | angiogenesis | - |
| GO:0006886 | IEA | - | intracellular protein transport | - |
| GO:0006915 | TAS | - | apoptotic process | 19637314 |
| GO:0007155 | ISS | - | cell adhesion | - |
| GO:0007266 | TAS | - | Rho protein signal transduction | 3888408 |
| GO:0008333 | IDA | - | endosome to lysosome transport | 10508588 |
| GO:0010595 | IMP | - | positive regulation of endothelial cell migration | 21347332 |
| GO:0030154 | IEA | - | cell differentiation | - |
| GO:0030168 | TAS | - | platelet activation | - |
| GO:0030334 | IGI | - | regulation of cell migration | 20460403 |
| GO:0030336 | IDA | - | negative regulation of cell migration | 20460403 |
| GO:0043065 | IMP | - | positive regulation of apoptotic process | 21373644 |
| GO:0043065 | ISS | - | positive regulation of apoptotic process | - |
| GO:0045766 | ISS | - | positive regulation of angiogenesis | - |
| GO:0045786 | ISS | - | negative regulation of cell cycle | - |
| GO:0051056 | TAS | - | regulation of small GTPase mediated signal transduction | - |
| GO:0061154 | IMP | - | endothelial tube morphogenesis | 21347332 |
| GO:0070301 | IDA | - | cellular response to hydrogen peroxide | 21373644 |
| GO:0071479 | IDA | - | cellular response to ionizing radiation | 21373644 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| CIT | RHOB | 106881 | 8543060 | Far Western; Two-hybrid |
| CIT | RHOB | 116290 | 8543060 | Far Western; Two-hybrid |
| ARHGDIG | RHOB | 106891 | 8939998 | Two-hybrid |
| ARHGDIG | RHOB | 106881 | 8939998 | Two-hybrid |
| PDE6D | RHOB | 111173 | 11786539 | Two-hybrid |
| PDE6D | RHOB | 106881 | 11786539 | Two-hybrid |
| ARHGEF3 | RHOB | 119115 | 12221096 | Biochemical Activity; Reconstituted Complex |
| ARHGEF3 | RHOB | 106881 | 12221096 | Biochemical Activity; Reconstituted Complex |
| RHPN2 | RHOB | 124521 | 12473120 | Affinity Capture-Western; Two-hybrid |
| RHPN2 | RHOB | 106881 | 12473120 | Affinity Capture-Western; Two-hybrid |
| No data |
| No data |



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