AutismKB 2.0

Annotation Details for FLG2


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Basic Information Top
Gene Symbol:FLG2 ( IFPS )
Gene Full Name: filaggrin family member 2
Band: 1q21.3
Quick LinksEntrez ID:388698; OMIM: NA; Uniprot ID:FILA2_HUMAN; ENSEMBL ID: ENSG00000143520; HGNC ID: 33276
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus21630459
GO:0005737IDA-cytoplasm19384417
GO:0070062IDA-extracellular exosome23376485
GO:1904724TAS-tertiary granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005198IEA-structural molecule activity-
GO:0005509IEA-calcium ion binding-
GO:0046914IEA-transition metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0043312TAS-neutrophil degranulation-
GO:0061436IEP-establishment of skin barrier23403047
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3645678
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018