AutismKB 2.0

Annotation Details for ARHGAP1


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Basic Information Top
Gene Symbol:ARHGAP1 ( CDC42GAP,RHOGAP,RHOGAP1,p50rhoGAP )
Gene Full Name: Rho GTPase activating protein 1
Band: 11p11.2
Quick LinksEntrez ID:392; OMIM: 602732; Uniprot ID:RHG01_HUMAN; ENSEMBL ID: ENSG00000175220; HGNC ID: 673
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm25468996
GO:0005829TAS-cytosol-
GO:0010008IDA-endosome membrane16380373
GO:0048471IDA-perinuclear region of cytoplasm16380373
GO:0070062IDA-extracellular exosome19056867
GO:0097443IMPcolocalizes_withsorting endosome16380373
GO ID Evidence Qualifier GO_term References
GO:0005070TAS-SH3/SH2 adaptor activity8253717
GO:0005096IDA-GTPase activator activity8253717
GO:0005096TAS-GTPase activator activity-
GO:0005515IPI-protein binding9262406
GO:0017124IEA-SH3 domain binding-
GO:0017137IPI-Rab GTPase binding16380373
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0007264IDA-small GTPase mediated signal transduction8253717
GO:0007266TAS-Rho protein signal transduction8253717
GO:0009967IEA-positive regulation of signal transduction-
GO:0032439IMP-endosome localization16380373
GO:0033572IMP-transferrin transport16380373
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0098706IMP-ferric iron import across plasma membrane16380373
GO:2001136IMP-negative regulation of endocytic recycling16380373
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ARHGAP1RHOA1068859407060 9535855 9548756 16189514 20660160 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
ARHGAP1RHOA1068809407060 9535855 9548756 16189514 20660160 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
ARHGAP1RHOC10688516189514 Two-hybrid
ARHGAP1RHOC10688216189514 Two-hybrid
PIK3R1ARHGAP11068858253717 Reconstituted Complex
PIK3R1ARHGAP11113138253717 Reconstituted Complex
SRCARHGAP11068858253717 Reconstituted Complex
SRCARHGAP11125928253717 Reconstituted Complex
CDC42ARHGAP11068859407060 9427749 9535855 10551883 Reconstituted Complex; Two-hybrid
CDC42ARHGAP11074339407060 9427749 9535855 10551883 Reconstituted Complex; Two-hybrid
RAC1ARHGAP11068859535855 Reconstituted Complex
RAC1ARHGAP11118179535855 Reconstituted Complex
BNIP2ARHGAP110688510551883 10954711 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
BNIP2ARHGAP110713110551883 10954711 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ARHGAP1ARHGAP110688510954711 Reconstituted Complex
BNIPLARHGAP110688512901880 Two-hybrid
BNIPLARHGAP112721112901880 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2445003
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050417-305'