Annotation Details for LBR

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Basic Information Top

Gene Symbol:	LBR ( DHCR14B,FLJ43126,LMN2R,MGC9041,PHA )
Gene Full Name:	lamin B receptor
Band:	1q42.12
Quick Links	Entrez ID:3930; OMIM: 600024; Uniprot ID:LBR_HUMAN; ENSEMBL ID: ENSG00000143815; HGNC ID: 6518
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:6 results
Molecular Function:7 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005635	TAS	-	nuclear envelope	-
GO:0005639	TAS	-	integral component of nuclear inner membrane	8157662
GO:0016020	IDA	-	membrane	19946888
GO:0016021	IDA	-	integral component of membrane	15698635
GO:0030176	IBA	NOT	integral component of endoplasmic reticulum membrane	-
GO:0031965	IDA	-	nuclear membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0003677	IEA	-	DNA binding	-
GO:0003723	IDA	-	RNA binding	22681889
GO:0005515	IPI	-	protein binding	8663349
GO:0005521	TAS	-	lamin binding	8157662
GO:0016627	IBA	-	oxidoreductase activity, acting on the CH-CH group of donors	-
GO:0050613	TAS	-	delta14-sterol reductase activity	-
GO:0070087	IPI	-	chromo shadow domain binding	15882967

GO ID	Evidence	Qualifier	GO_term	References
GO:0006695	TAS	-	cholesterol biosynthetic process	-
GO:0016126	IBA	-	sterol biosynthetic process	-
GO:0055114	IEA	-	oxidation-reduction process	-

Protein-Protein Interaction

BioGRID:12 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
CBX5	LBR	117030	8663349 15882967	Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
CBX5	LBR	110122	8663349 15882967	Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
CBX3	LBR	110122	8663349	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CBX3	LBR	116463	8663349	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FNBP4	LBR	110122	10744724	Reconstituted Complex
FNBP4	LBR	116941	10744724	Reconstituted Complex
AKAP8L	LBR	110122	11034899	Affinity Capture-Western
AKAP8L	LBR	117940	11034899	Affinity Capture-Western
YWHAG	LBR	110122	17353931	Affinity Capture-MS
YWHAG	LBR	113364	17353931	Affinity Capture-MS
MECP2	LBR	110122	19331822	Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
MECP2	LBR	110368	19331822	Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:2138281
Data Attributes: MGI curated and HomoloGene calculated