AutismKB 2.0

Annotation Details for LCAT


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Basic Information Top
Gene Symbol:LCAT ( - )
Gene Full Name: lecithin-cholesterol acyltransferase
Band: 16q22.1
Quick LinksEntrez ID:3931; OMIM: 606967; Uniprot ID:LCAT_HUMAN; ENSEMBL ID: ENSG00000213398; HGNC ID: 6522
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space3458198
GO:0034364IDA-high-density lipoprotein particle3104518
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004607IDA-phosphatidylcholine-sterol O-acyltransferase activity4335615
GO:0004607NAS-phosphatidylcholine-sterol O-acyltransferase activity11966470
GO:0004607TAS-phosphatidylcholine-sterol O-acyltransferase activity-
GO:0005515IPI-protein binding11435418
GO:0034186IPI-apolipoprotein A-I binding1587806
GO ID Evidence Qualifier GO_term References
GO:0006644IDA-phospholipid metabolic process4335615
GO:0006656IDA-phosphatidylcholine biosynthetic process11966470
GO:0008203IDA-cholesterol metabolic process4335615
GO:0030301IDA-cholesterol transport10559507
GO:0034372IDA-very-low-density lipoprotein particle remodeling15654758
GO:0034375IDA-high-density lipoprotein particle remodeling4335615
GO:0034375TAS-high-density lipoprotein particle remodeling-
GO:0034435IDA-cholesterol esterification3458198
GO:0042158IEA-lipoprotein biosynthetic process-
GO:0042632IDA-cholesterol homeostasis4335615
GO:0043691IDA-reverse cholesterol transport4335615
GO:0046470IDA-phosphatidylcholine metabolic process26195816
GO:0090107IEA-regulation of high-density lipoprotein particle assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LCATA2M10652411435418 Affinity Capture-Western; Reconstituted Complex
LCATA2M11012311435418 Affinity Capture-Western; Reconstituted Complex
LCATAPOA11101231644835 Reconstituted Complex
LCATAPOA11068321644835 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96755
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010716-3'