AutismKB 2.0

Annotation Details for LCN2


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Basic Information Top
Gene Symbol:LCN2 ( 24p3,MSFI,NGAL )
Gene Full Name: lipocalin 2
Band: 9q34.11
Quick LinksEntrez ID:3934; OMIM: 600181; Uniprot ID:NGAL_HUMAN; ENSEMBL ID: ENSG00000148346; HGNC ID: 6526
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576ISS-extracellular region-
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space16502470
GO:0005829IEA-cytosol-
GO:0035580TAS-specific granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0002020IEA-protease binding-
GO:0005215IEA-transporter activity-
GO:0005506ISS-iron ion binding-
GO:0036094IEA-small molecule binding-
GO:0042803IEA-protein homodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0006811IEA-ion transport-
GO:0006879TAS-cellular iron ion homeostasis-
GO:0009615IEA-response to virus-
GO:0009635IEA-response to herbicide-
GO:0010046IEA-response to mycotoxin-
GO:0010628IEA-positive regulation of gene expression-
GO:0015891ISS-siderophore transport-
GO:0019730TAS-antimicrobial humoral response-
GO:0031346IEA-positive regulation of cell projection organization-
GO:0031669IEA-cellular response to nutrient levels-
GO:0042493IEA-response to drug-
GO:0043312TAS-neutrophil degranulation-
GO:0045087ISS-innate immune response-
GO:0070207IEA-protein homotrimerization-
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071347IEA-cellular response to interleukin-1-
GO:0071356IEA-cellular response to tumor necrosis factor-
GO:0097192IEA-extrinsic apoptotic signaling pathway in absence of ligand-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LCN2LCN21101267683678 Affinity Capture-Western
MMP2LCN21101267683678 Affinity Capture-Western
MMP2LCN21104577683678 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96757
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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