Gene Symbol:	LCP2 ( SLP-76,SLP76 )
Gene Full Name:	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Band:	5q35.1
Quick Links	Entrez ID:3937; OMIM: 601603; Uniprot ID:LCP2_HUMAN; ENSEMBL ID: ENSG00000043462; HGNC ID: 6529
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005829	IDA	-	cytosol	20551903
GO:0005829	TAS	-	cytosol	-
GO:0005911	IEA	-	cell-cell junction	-
GO:0036398	IDA	-	TCR signalosome	20551903
GO:0044853	IDA	-	plasma membrane raft	20551903

GO ID	Evidence	Qualifier	GO_term	References
GO:0006955	TAS	-	immune response	7706237
GO:0007169	TAS	-	transmembrane receptor protein tyrosine kinase signaling pathway	7706237
GO:0030168	TAS	-	platelet activation	-
GO:0035556	IBA	-	intracellular signal transduction	-
GO:0038095	TAS	-	Fc-epsilon receptor signaling pathway	-
GO:0045576	IEA	-	mast cell activation	-
GO:0045860	IEP	-	positive regulation of protein kinase activity	14624253
GO:0050663	IEA	-	cytokine secretion	-
GO:0050852	IDA	-	T cell receptor signaling pathway	20551903
GO:0050852	TAS	-	T cell receptor signaling pathway	-

Gene Symbol	Interactant	Interaction ID	References	Description
LCP2	CBL	107315	10204582 10477741	Affinity Capture-Western
LCP2	CBL	110129	10204582 10477741	Affinity Capture-Western
LCP2	GRB2	109142	8695800 8995445 10204582 10224278 11314042 20936779	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LCP2	GRB2	110129	8695800 8995445 10204582 10224278 11314042 20936779	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LCP2	ITK	109907	10636929 15388330	Affinity Capture-Western; Reconstituted Complex
LCP2	ITK	110129	10636929 15388330	Affinity Capture-Western; Reconstituted Complex
VAV1	LCP2	113252	8703037 9047237	Affinity Capture-Western; Reconstituted Complex
VAV1	LCP2	110129	8703037 9047237	Affinity Capture-Western; Reconstituted Complex
PTPN6	LCP2	111742	8760799 9765283	Affinity Capture-Western; Reconstituted Complex
PTPN6	LCP2	110129	8760799 9765283	Affinity Capture-Western; Reconstituted Complex
ZAP70	LCP2	113367	9047237	Biochemical Activity
ZAP70	LCP2	110129	9047237	Biochemical Activity
GRAP2	LCP2	114799	10021361 10224278 10820259 16189514	Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
GRAP2	LCP2	110129	10021361 10224278 10820259 16189514	Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
LYN	LCP2	110129	10026222	Affinity Capture-Western; Reconstituted Complex
LYN	LCP2	110245	10026222	Affinity Capture-Western; Reconstituted Complex
NCK1	LCP2	110770	10229072 15388330	Affinity Capture-Western; Reconstituted Complex
NCK1	LCP2	110129	10229072 15388330	Affinity Capture-Western; Reconstituted Complex
WAS	LCP2	113293	10747096	Affinity Capture-Western
WAS	LCP2	110129	10747096	Affinity Capture-Western
TRAT1	LCP2	119154	10790433	Reconstituted Complex
TRAT1	LCP2	110129	10790433	Reconstituted Complex
PAG1	LCP2	110129	10790433	Reconstituted Complex
PAG1	LCP2	120931	10790433	Reconstituted Complex
PRAM1	LCP2	110129	11301322	Affinity Capture-Western
PRAM1	LCP2	123894	11301322	Affinity Capture-Western
PLCG1	LCP2	111351	11390650	Affinity Capture-Western; Reconstituted Complex
PLCG1	LCP2	110129	11390650	Affinity Capture-Western; Reconstituted Complex
SHB	LCP2	112358	12084069	Affinity Capture-Western; Reconstituted Complex
SHB	LCP2	110129	12084069	Affinity Capture-Western; Reconstituted Complex
PIK3R1	LCP2	110129	15388330	Affinity Capture-Western; Two-hybrid
PIK3R1	LCP2	111313	15388330	Affinity Capture-Western; Two-hybrid
YWHAZ	LCP2	113366	20936779	Two-hybrid
YWHAZ	LCP2	110129	20936779	Two-hybrid

AutismKB 2.0

Annotation Details for LCP2

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics