Gene Symbol:	LGALS1 ( DKFZp686E23103,GAL1,GBP )
Gene Full Name:	lectin, galactoside-binding, soluble, 1
Band:	22q13.1
Quick Links	Entrez ID:3956; OMIM: 150570; Uniprot ID:LEG1_HUMAN; ENSEMBL ID: ENSG00000100097; HGNC ID: 6561
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005578	IEA	-	proteinaceous extracellular matrix	-
GO:0005615	IDA	-	extracellular space	20551380
GO:0005622	IDA	-	intracellular	-
GO:0005634	IEA	-	nucleus	-
GO:0005737	TAS	-	cytoplasm	16130169
GO:0005788	TAS	-	endoplasmic reticulum lumen	-
GO:0005829	IEA	-	cytosol	-
GO:0009986	IEA	-	cell surface	-
GO:0031012	IDA	-	extracellular matrix	23979707
GO:0031012	IDA	colocalizes_with	extracellular matrix	20551380
GO:0031012	ISS	colocalizes_with	extracellular matrix	22261194
GO:0070062	IDA	-	extracellular exosome	23376485

GO ID	Evidence	Qualifier	GO_term	References
GO:0001948	IEA	-	glycoprotein binding	-
GO:0003723	IDA	-	RNA binding	22658674
GO:0004871	IMP	-	signal transducer activity	12761501
GO:0005515	IPI	-	protein binding	10369126
GO:0030395	IEA	-	lactose binding	-
GO:0042803	IEA	-	protein homodimerization activity	-
GO:0043236	IEA	-	laminin binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0002317	IEA	-	plasma cell differentiation	-
GO:0006915	IEA	-	apoptotic process	-
GO:0007165	IEA	-	signal transduction	-
GO:0010812	IEA	-	negative regulation of cell-substrate adhesion	-
GO:0010977	IEA	-	negative regulation of neuron projection development	-
GO:0031295	IEA	-	T cell costimulation	-
GO:0034120	IEA	-	positive regulation of erythrocyte aggregation	-
GO:0035900	IEA	-	response to isolation stress	-
GO:0042493	IEA	-	response to drug	-
GO:0042981	TAS	-	regulation of apoptotic process	16130169
GO:0043123	IMP	-	positive regulation of I-kappaB kinase/NF-kappaB signaling	12761501
GO:0043687	TAS	-	post-translational protein modification	-
GO:0044267	TAS	-	cellular protein metabolic process	-
GO:0045445	IEA	-	myoblast differentiation	-
GO:0046598	IDA	-	positive regulation of viral entry into host cell	21670307
GO:0048678	IEA	-	response to axon injury	-
GO:0071333	IEA	-	cellular response to glucose stimulus	-
GO:0071407	IEA	-	cellular response to organic cyclic compound	-
GO:2001200	IDA	NOT	positive regulation of dendritic cell differentiation	16116184

Gene Symbol	Interactant	Interaction ID	References	Description
LGALS1	CD2	110147	10642604	Affinity Capture-Western
LGALS1	CD2	107352	10642604	Affinity Capture-Western
LGALS1	CD4	107358	10490978	Affinity Capture-Western
LGALS1	CD4	110147	10490978	Affinity Capture-Western
LGALS1	CD7	107362	10490978	Affinity Capture-Western
LGALS1	CD7	110147	10490978	Affinity Capture-Western
LGALS1	HRAS	109501	11709720	Affinity Capture-MS; Affinity Capture-Western
LGALS1	HRAS	110147	11709720	Affinity Capture-MS; Affinity Capture-Western
PTPRC	LGALS1	111752	10490978	Affinity Capture-Western
PTPRC	LGALS1	110147	10490978	Affinity Capture-Western
SPN	LGALS1	112571	10490978	Affinity Capture-Western
SPN	LGALS1	110147	10490978	Affinity Capture-Western
LGALS3BP	LGALS1	110150	11146440	Reconstituted Complex
LGALS3BP	LGALS1	110147	11146440	Reconstituted Complex
LGALS3	LGALS1	110149	11522829	Affinity Capture-Western
LGALS3	LGALS1	110147	11522829	Affinity Capture-Western
SMN1	LGALS1	112490	11522829	Affinity Capture-Western
SMN1	LGALS1	110147	11522829	Affinity Capture-Western
SNRPB	LGALS1	112512	11522829	Affinity Capture-Western
SNRPB	LGALS1	110147	11522829	Affinity Capture-Western
SIP1	LGALS1	114059	11522829	Affinity Capture-Western
SIP1	LGALS1	110147	11522829	Affinity Capture-Western
GEMIN4	LGALS1	119102	11522829	Reconstituted Complex; Two-hybrid
GEMIN4	LGALS1	110147	11522829	Reconstituted Complex; Two-hybrid
MUC16	LGALS1	110147	12615972	Affinity Capture-Western
MUC16	LGALS1	125094	12615972	Affinity Capture-Western
SUSD2	LGALS1	121109	17353931	Affinity Capture-MS
SUSD2	LGALS1	110147	17353931	Affinity Capture-MS

AutismKB 2.0

Annotation Details for LGALS1