AutismKB 2.0

Annotation Details for LHX1


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Basic Information Top
Gene Symbol:LHX1 ( LIM-1,LIM1,MGC126723,MGC138141 )
Gene Full Name: LIM homeobox 1
Band: 17q12
Quick LinksEntrez ID:3975; OMIM: 601999; Uniprot ID:LHX1_HUMAN; ENSEMBL ID: ENSG00000132130; HGNC ID: 6593
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634ISS-nucleus-
GO:0043234ISS-protein complex-
GO ID Evidence Qualifier GO_term References
GO:0003700ISS-transcription factor activity, sequence-specific DNA binding-
GO:0003714ISS-transcription corepressor activity-
GO:0043565IEA-sequence-specific DNA binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001655ISS-urogenital system development-
GO:0001657ISS-ureteric bud development-
GO:0001658IEA-branching involved in ureteric bud morphogenesis-
GO:0001702ISS-gastrulation with mouth forming second-
GO:0001705ISS-ectoderm formation-
GO:0001706ISS-endoderm formation-
GO:0001822ISS-kidney development-
GO:0006366ISS-transcription from RNA polymerase II promoter-
GO:0007267ISS-cell-cell signaling-
GO:0007389ISS-pattern specification process-
GO:0007399TAS-nervous system development9212161
GO:0008045ISS-motor neuron axon guidance-
GO:0009653ISS-anatomical structure morphogenesis-
GO:0009791ISS-post-embryonic development-
GO:0009880ISS-embryonic pattern specification-
GO:0009887TAS-animal organ morphogenesis7700351
GO:0009948ISS-anterior/posterior axis specification-
GO:0009952ISS-anterior/posterior pattern specification-
GO:0009953ISS-dorsal/ventral pattern formation-
GO:0010468ISS-regulation of gene expression-
GO:0010842ISS-retina layer formation-
GO:0021517IEA-ventral spinal cord development-
GO:0021527ISS-spinal cord association neuron differentiation-
GO:0021537IEA-telencephalon development-
GO:0021549ISS-cerebellum development-
GO:0021702ISS-cerebellar Purkinje cell differentiation-
GO:0021871ISS-forebrain regionalization-
GO:0021937ISS-cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation-
GO:0032525IEA-somite rostral/caudal axis specification-
GO:0035502IEA-metanephric part of ureteric bud development-
GO:0035846ISS-oviduct epithelium development-
GO:0035847ISS-uterine epithelium development-
GO:0035849IEA-nephric duct elongation-
GO:0035852IEA-horizontal cell localization-
GO:0040019ISS-positive regulation of embryonic development-
GO:0044344IEA-cellular response to fibroblast growth factor stimulus-
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0048646ISS-anatomical structure formation involved in morphogenesis-
GO:0048703ISS-embryonic viscerocranium morphogenesis-
GO:0048793IEA-pronephros development-
GO:0060059ISS-embryonic retina morphogenesis in camera-type eye-
GO:0060065ISS-uterus development-
GO:0060066ISS-oviduct development-
GO:0060067ISS-cervix development-
GO:0060068ISS-vagina development-
GO:0060322ISS-head development-
GO:0060429ISS-epithelium development-
GO:0061205ISS-paramesonephric duct development-
GO:0072049ISS-comma-shaped body morphogenesis-
GO:0072050ISS-S-shaped body morphogenesis-
GO:0072077ISS-renal vesicle morphogenesis-
GO:0072177IEA-mesonephric duct development-
GO:0072178ISS-nephric duct morphogenesis-
GO:0072224IEA-metanephric glomerulus development-
GO:0072278IEA-metanephric comma-shaped body morphogenesis-
GO:0072283IEA-metanephric renal vesicle morphogenesis-
GO:0072284IEA-metanephric S-shaped body morphogenesis-
GO:0090009ISS-primitive streak formation-
GO:0090190ISS-positive regulation of branching involved in ureteric bud morphogenesis-
GO:0097477ISS-lateral motor column neuron migration-
GO:2000543ISS-positive regulation of gastrulation-
GO:2000744ISS-positive regulation of anterior head development-
GO:2000768ISS-positive regulation of nephron tubule epithelial cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LHX1FOXA211016312642491 Reconstituted Complex
LHX1FOXA210941212642491 Reconstituted Complex
LHX3LHX11101639452425 Reconstituted Complex
LHX3LHX11137189452425 Reconstituted Complex
OTX2LHX111105510623575 Reconstituted Complex
OTX2LHX111016310623575 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99783
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-116'