Annotation Details for LIFR


Gene Symbol: | LIFR ( CD118,FLJ98106,FLJ99923,LIF-R,SJS2,STWS,SWS ) |
---|---|
Gene Full Name: | leukemia inhibitory factor receptor alpha |
Band: | 5p13.1 |
Quick Links | Entrez ID:3977; OMIM: 151443; Uniprot ID:LIFR_HUMAN; ENSEMBL ID: ENSG00000113594; HGNC ID: 6597 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005615 | IEA | - | extracellular space | - |
GO:0005886 | TAS | - | plasma membrane | - |
GO:0005887 | TAS | - | integral component of plasma membrane | 1915266 |
GO:0043235 | IDA | - | receptor complex | 8999038 |
GO:0070062 | IDA | - | extracellular exosome | 23533145 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004897 | IDA | contributes_to | ciliary neurotrophic factor receptor activity | 12643274 |
GO:0004923 | IDA | - | leukemia inhibitory factor receptor activity | 7957045 |
GO:0004923 | IDA | contributes_to | leukemia inhibitory factor receptor activity | 8999038 |
GO:0004924 | IDA | contributes_to | oncostatin-M receptor activity | 8999038 |
GO:0005127 | IPI | - | ciliary neurotrophic factor receptor binding | 12707266 |
GO:0005515 | IPI | - | protein binding | 16051226 |
GO:0019838 | IPI | - | growth factor binding | 8999038 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0007166 | TAS | - | cell surface receptor signaling pathway | 1915266 |
GO:0008284 | IDA | - | positive regulation of cell proliferation | 7957045 |
GO:0019221 | IDA | - | cytokine-mediated signaling pathway | 7957045 |
GO:0034097 | IDA | - | response to cytokine | 8999038 |
GO:0038165 | IMP | - | oncostatin-M-mediated signaling pathway | 8999038 |
GO:0048861 | IDA | - | leukemia inhibitory factor signaling pathway | 8999038 |
GO:0070120 | IDA | - | ciliary neurotrophic factor-mediated signaling pathway | 12643274 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
LIFR | CNTFR | 110165 | 11943154 12707266 | Affinity Capture-Western; Reconstituted Complex |
LIFR | CNTFR | 107671 | 11943154 12707266 | Affinity Capture-Western; Reconstituted Complex |
LIFR | IL6ST | 110165 | 8999038 12047380 | Affinity Capture-Western |
LIFR | IL6ST | 109786 | 8999038 12047380 | Affinity Capture-Western |
LIFR | LIF | 110164 | 12601009 | Reconstituted Complex |
LIFR | LIF | 110165 | 12601009 | Reconstituted Complex |
OSM | LIFR | 111049 | 1536831 | Affinity Capture-Western |
OSM | LIFR | 110165 | 1536831 | Affinity Capture-Western |
PTPN6 | LIFR | 111742 | 10800945 | Affinity Capture-Western |
PTPN6 | LIFR | 110165 | 10800945 | Affinity Capture-Western |
No data |
No data |
- MGI ID: MGI:96788
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-050327-16