AutismKB 2.0

Annotation Details for LIG1


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Basic Information Top
Gene Symbol:LIG1 ( MGC117397,MGC130025 )
Gene Full Name: ligase I, DNA, ATP-dependent
Band: 19q13.33
Quick LinksEntrez ID:3978; OMIM: 126391; Uniprot ID:DNLI1_HUMAN; ENSEMBL ID: ENSG00000105486; HGNC ID: 6598
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus8696349
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005739IBA-mitochondrion-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003909IDA-DNA ligase activity9809069
GO:0003909IMP-DNA ligase activity15871698
GO:0003909TAS-DNA ligase activity-
GO:0003910IBA-DNA ligase (ATP) activity-
GO:0005524IEA-ATP binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006259TAS-DNA metabolic process2204063
GO:0006266TAS-DNA ligation-
GO:0006281TAS-DNA repair8696349
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006284IDA-base-excision repair19589734
GO:0006297TAS-nucleotide-excision repair, DNA gap filling-
GO:0006298TAS-mismatch repair-
GO:0009653TAS-anatomical structure morphogenesis8696349
GO:0033151IDANOTV(D)J recombination9809069
GO:0051103IBANOTDNA ligation involved in DNA repair-
GO:0051301IEA-cell division-
GO:0071897IEA-DNA biosynthetic process-
GO:1903461IBA-Okazaki fragment processing involved in mitotic DNA replication-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MRE11ALIG11101668530104 Two-hybrid
MRE11ALIG11105018530104 Two-hybrid
PCNALIG111114212171929 Affinity Capture-MS
PCNALIG111016612171929 Affinity Capture-MS
UBCLIG111016618655026 Affinity Capture-MS
UBCLIG111316418655026 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:101789
  • Data Attributes: MGI curated and HomoloGene calculated
No data