Annotation Details for LMX1B

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Basic Information Top

Gene Symbol:	LMX1B ( LMX1.2,MGC138325,MGC142051,NPS1 )
Gene Full Name:	LIM homeobox transcription factor 1, beta
Band:	9q33.3
Quick Links	Entrez ID:4010; OMIM: 602575; Uniprot ID:LMX1B_HUMAN; ENSEMBL ID: ENSG00000136944; HGNC ID: 6654
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:1 results
Molecular Function:5 results
Biological Process:9 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IDA	-	nucleus	10767331

GO ID	Evidence	Qualifier	GO_term	References
GO:0000977	ISS	-	RNA polymerase II regulatory region sequence-specific DNA binding	-
GO:0000983	ISS	-	transcription factor activity, RNA polymerase II core promoter sequence-specific	-
GO:0003700	IDA	-	transcription factor activity, sequence-specific DNA binding	10767331
GO:0005515	IPI	-	protein binding	12792813
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001701	NAS	-	in utero embryonic development	12792813
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0006355	IDA	-	regulation of transcription, DNA-templated	10767331
GO:0007275	NAS	-	multicellular organism development	9590287
GO:0009953	ISS	-	dorsal/ventral pattern formation	-
GO:0030182	ISS	-	neuron differentiation	-
GO:0045944	ISS	-	positive regulation of transcription from RNA polymerase II promoter	-
GO:0045944	TAS	-	positive regulation of transcription from RNA polymerase II promoter	24431302
GO:0071542	ISS	-	dopaminergic neuron differentiation	-

Protein-Protein Interaction

BioGRID:2 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
SSBP3	LMX1B	117175	20211142	Two-hybrid
SSBP3	LMX1B	110195	20211142	Two-hybrid

AlzGene, PDGene and SZGene

Alz Gene:0 results
PD Gene:1 results
SZ Gene:1 results

Gene Symbol	Poly Names	Gene overview in PDGene
LMX1B	rs10121915, rs10448285, rs10733682, rs10760442, rs10760443, rs10760446, rs10760450, rs10819195, rs10987379, rs10987385, rs10987386, rs10987413, rs12336217, rs12343574, rs12555176, rs12555734, rs13285227, rs13295990, rs2235055, rs2277158, rs3737048, rs3814120, rs3829849, rs4073436, rs4322101, rs4836551, rs4837104, rs6478750, rs7853174, rs7854658, rs7857133, rs7864957, rs7874639, rs7874916, rs867559, rs870956	Gene overview in PDGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1100513
Data Attributes: MGI curated and HomoloGene calculated