AutismKB 2.0

Annotation Details for LRP2


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Basic Information Top
Gene Symbol:LRP2 ( DBS,GP330 )
Gene Full Name: low density lipoprotein receptor-related protein 2
Band: 2q31.1
Quick LinksEntrez ID:4036; OMIM: 600073; Uniprot ID:LRP2_HUMAN; ENSEMBL ID: ENSG00000081479; HGNC ID: 6694
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005764TAS-lysosome7768901
GO:0005765IDA-lysosomal membrane17897319
GO:0005768IEA-endosome-
GO:0005783IEA-endoplasmic reticulum-
GO:0005794IEA-Golgi apparatus-
GO:0005886TAS-plasma membrane-
GO:0005905IEA-clathrin-coated pit-
GO:0016021IEA-integral component of membrane-
GO:0016324ISS-apical plasma membrane-
GO:0030139IEA-endocytic vesicle-
GO:0030665TAS-clathrin-coated vesicle membrane-
GO:0031526IEA-brush border membrane-
GO:0043235IDA-receptor complex23382219
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005041TAS-low-density lipoprotein receptor activity-
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding9773776
GO:0017124IEA-SH3 domain binding-
GO:0042954TAS-lipoprotein transporter activity-
GO:0051087IPI-chaperone binding9228033
GO ID Evidence Qualifier GO_term References
GO:0001523TAS-retinoid metabolic process-
GO:0003281IEA-ventricular septum development-
GO:0006629TAS-lipid metabolic process7768901
GO:0006897TAS-endocytosis7768901
GO:0006898IEA-receptor-mediated endocytosis-
GO:0008283IEA-cell proliferation-
GO:0030900IEA-forebrain development-
GO:0035904IEA-aorta development-
GO:0042359TAS-vitamin D metabolic process-
GO:0042953IEA-lipoprotein transport-
GO:0060976IEA-coronary vasculature development-
GO:0061024TAS-membrane organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LRP2APBA211021610827173 Two-hybrid
LRP2APBA210681810827173 Two-hybrid
LRP2APOE1102167768901 Reconstituted Complex
LRP2APOE1068457768901 Reconstituted Complex
LRP2APOH1102169727058 Reconstituted Complex
LRP2APOH1068479727058 Reconstituted Complex
LRP2CLU1076037768901 Reconstituted Complex
LRP2CLU1102167768901 Reconstituted Complex
LRP2DAB111021610827173 12508107 Reconstituted Complex; Two-hybrid
LRP2DAB110797010827173 12508107 Reconstituted Complex; Two-hybrid
LRP2DAB211021610769163 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRP2DAB210797110769163 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRP2DLG210808412713445 Two-hybrid
LRP2DLG211021612713445 Two-hybrid
LRP2DLG311021612713445 Two-hybrid
LRP2DLG310808512713445 Two-hybrid
LRP2DLG411021610827173 12713445 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRP2DLG410808610827173 12713445 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRP2GC11021611717447 Affinity Capture-Western
LRP2GC10890811717447 Affinity Capture-Western
LRP2LPA11021610073957 Reconstituted Complex
LRP2LPA11020210073957 Reconstituted Complex
LRP2LPL1102167686151 Reconstituted Complex
LRP2LPL1102057686151 Reconstituted Complex
LRPAP1LRP21102167512726 11912251 Reconstituted Complex
LRPAP1LRP21102217512726 11912251 Reconstituted Complex
THBS1LRP21102167775583 Reconstituted Complex
THBS1LRP21129157775583 Reconstituted Complex
PLAULRP21102168344937 Reconstituted Complex
PLAULRP21113448344937 Reconstituted Complex
RBP1LRP211021610203351 Reconstituted Complex
RBP1LRP211188110203351 Reconstituted Complex
GIPC1LRP211021610827173 11912251 12508107 Reconstituted Complex; Two-hybrid
GIPC1LRP211597810827173 11912251 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP2LRP211021610827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP2LRP211708610827173 12508107 Reconstituted Complex; Two-hybrid
SYNJ2BPLRP211021610827173 Reconstituted Complex; Two-hybrid
SYNJ2BPLRP212061410827173 Reconstituted Complex; Two-hybrid
ITGB1BP1LRP211021610827173 Reconstituted Complex; Two-hybrid
ITGB1BP1LRP211468910827173 Reconstituted Complex; Two-hybrid
MAPK8IP1LRP211021610827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP1LRP211486410827173 12508107 Reconstituted Complex; Two-hybrid
NOS1APLRP211021610827173 Reconstituted Complex; Two-hybrid
NOS1APLRP211507110827173 Reconstituted Complex; Two-hybrid
ANAPC10LRP211021610827173 Two-hybrid
ANAPC10LRP211566510827173 Two-hybrid
SCN3ALRP211021610827173 Two-hybrid
SCN3ALRP211223310827173 Two-hybrid
ANKRA2LRP211021611095640 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ANKRA2LRP212175811095640 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAGI1LRP211021611274227 Reconstituted Complex; Two-hybrid
MAGI1LRP211465511274227 Reconstituted Complex; Two-hybrid
SCGB1A1LRP211021611278724 Reconstituted Complex
SCGB1A1LRP211320311278724 Reconstituted Complex
SNX17LRP211021612169628 Reconstituted Complex
SNX17LRP211512812169628 Reconstituted Complex
LRP2BPLRP211021612508107 Reconstituted Complex; Two-hybrid
LRP2BPLRP212091612508107 Reconstituted Complex; Two-hybrid
ANKS1BLRP211021612508107 Two-hybrid
ANKS1BLRP212122912508107 Two-hybrid
LDLRAP1LRP211021614528014 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LDLRAP1LRP211756114528014 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
LRP2rs2075252, rs3755166 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:95794
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050119-2'