Gene Symbol:	LRP4 ( CLSS,KIAA0816,LRP-4,LRP10,MEGF7 )
Gene Full Name:	low density lipoprotein receptor-related protein 4
Band:	11p11.2
Quick Links	Entrez ID:4038; OMIM: 604270; Uniprot ID:LRP4_HUMAN; ENSEMBL ID: ENSG00000134569; HGNC ID: 6696
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005886	IBA	-	plasma membrane	-
GO:0009986	IDA	-	cell surface	20381006
GO:0009986	ISS	-	cell surface	-
GO:0014069	ISS	-	postsynaptic density	-
GO:0016021	IEA	-	integral component of membrane	-
GO:0016600	ISS	colocalizes_with	flotillin complex	-
GO:0030425	ISS	-	dendrite	-
GO:0031594	ISS	-	neuromuscular junction	-
GO:0043025	ISS	-	neuronal cell body	-
GO:0043235	IBA	-	receptor complex	-
GO:0097060	ISS	-	synaptic membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0005509	IEA	-	calcium ion binding	-
GO:0005515	IPI	-	protein binding	21471202
GO:0017147	IBA	-	Wnt-protein binding	-
GO:0030971	ISS	-	receptor tyrosine kinase binding	-
GO:0034185	IEA	-	apolipoprotein binding	-
GO:0042803	IEA	-	protein homodimerization activity	-
GO:0042813	IBA	-	Wnt-activated receptor activity	-
GO:0097110	ISS	-	scaffold protein binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001822	IDA	-	kidney development	20381006
GO:0001942	IEA	-	hair follicle development	-
GO:0006897	IEA	-	endocytosis	-
GO:0009954	IEA	-	proximal/distal pattern formation	-
GO:0030279	IMP	-	negative regulation of ossification	21471202
GO:0030509	IEA	-	BMP signaling pathway	-
GO:0042475	IEA	-	odontogenesis of dentin-containing tooth	-
GO:0042733	IEA	-	embryonic digit morphogenesis	-
GO:0044332	IBA	-	Wnt signaling pathway involved in dorsal/ventral axis specification	-
GO:0048813	ISS	-	dendrite morphogenesis	-
GO:0050731	IEA	-	positive regulation of peptidyl-tyrosine phosphorylation	-
GO:0050771	ISS	-	negative regulation of axonogenesis	-
GO:0050808	ISS	-	synapse organization	-
GO:0051124	ISS	-	synaptic growth at neuromuscular junction	-
GO:0051290	ISS	-	protein heterotetramerization	-
GO:0060173	IDA	-	limb development	20381006
GO:0071340	ISS	-	skeletal muscle acetylcholine-gated channel clustering	-
GO:0090090	IDA	-	negative regulation of canonical Wnt signaling pathway	20093106
GO:0090090	IMP	-	negative regulation of canonical Wnt signaling pathway	20381006
GO:0097104	ISS	-	postsynaptic membrane assembly	-
GO:0097105	ISS	-	presynaptic membrane assembly	-
GO:1901631	ISS	-	positive regulation of presynaptic membrane organization	-
GO:1904395	IEA	-	positive regulation of skeletal muscle acetylcholine-gated channel clustering	-

Gene Symbol	Interactant	Interaction ID	References	Description
SUMO1	LRP4	110218	17549794	Affinity Capture-MS
SUMO1	LRP4	113188	17549794	Affinity Capture-MS

AutismKB 2.0

Annotation Details for LRP4