AutismKB 2.0

Annotation Details for LRPAP1


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Basic Information Top
Gene Symbol:LRPAP1 ( A2MRAP,A2RAP,HBP44,MGC138272,MRAP,RAP )
Gene Full Name: low density lipoprotein receptor-related protein associated protein 1
Band: 4p16.3
Quick LinksEntrez ID:4043; OMIM: 104225; Uniprot ID:AMRP_HUMAN; ENSEMBL ID: ENSG00000163956; HGNC ID: 6701
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region14645246
GO:0005768IDA-endosome7774585
GO:0005783IDA-endoplasmic reticulum-
GO:0005793IDA-endoplasmic reticulum-Golgi intermediate compartment7774585
GO:0005794IDA-Golgi apparatus7774585
GO:0005796IEA-Golgi lumen-
GO:0005801IDA-cis-Golgi network7774585
GO:0005886IDA-plasma membrane16263759
GO:0009986IEA-cell surface-
GO:0031904IEA-endosome lumen-
GO:0048237IDA-rough endoplasmic reticulum lumen7774585
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding14645246
GO:0005515IPI-protein binding8083232
GO:0008201IEA-heparin binding-
GO:0035473IEA-lipase binding-
GO:0048019IDA-receptor antagonist activity8083232
GO:0048019TAS-receptor antagonist activity14645246
GO:0050750IDA-low-density lipoprotein particle receptor binding7774585
GO:0050750TAS-low-density lipoprotein particle receptor binding21289173
GO:0070326IPI-very-low-density lipoprotein particle receptor binding8083232
GO ID Evidence Qualifier GO_term References
GO:0010916IDA-negative regulation of very-low-density lipoprotein particle clearance8083232
GO:0032091IDA-negative regulation of protein binding8083232
GO:0048259IDA-regulation of receptor-mediated endocytosis7774585
GO:1900116TAS-extracellular negative regulation of signal transduction14645246
GO:1900222IGI-negative regulation of amyloid-beta clearance19098903
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LRPAP1EIF4EBP111022116798736 Affinity Capture-Western
LRPAP1EIF4EBP110829316798736 Affinity Capture-Western
LRPAP1MTOR10875716798736 Affinity Capture-Western
LRPAP1MTOR11022116798736 Affinity Capture-Western
LRPAP1LDLR1101417822276 Reconstituted Complex
LRPAP1LDLR1102217822276 Reconstituted Complex
LRPAP1LRP11102151374383 Reconstituted Complex
LRPAP1LRP11102211374383 Reconstituted Complex
LRPAP1LRP21102167512726 11912251 Reconstituted Complex
LRPAP1LRP21102217512726 11912251 Reconstituted Complex
SORL1LRPAP11125368940146 11557679 Co-purification; Reconstituted Complex
SORL1LRPAP11102218940146 11557679 Co-purification; Reconstituted Complex
SORT1LRPAP11121809013611 Reconstituted Complex
SORT1LRPAP11102219013611 Reconstituted Complex
VLDLRLRPAP111327710571241 12899622 Reconstituted Complex
VLDLRLRPAP111022110571241 12899622 Reconstituted Complex
RAF1LRPAP111183110783161 Two-hybrid
RAF1LRPAP111022110783161 Two-hybrid
RALGDSLRPAP111022110783161 Two-hybrid
RALGDSLRPAP111183610783161 Two-hybrid
RALALRPAP111022111167825 Reconstituted Complex
RALALRPAP111183411167825 Reconstituted Complex
LRP8LRPAP111357912899622 Reconstituted Complex
LRP8LRPAP111022112899622 Reconstituted Complex
POLA2LRPAP111717616169070 Two-hybrid
POLA2LRPAP111022116169070 Two-hybrid
RTN4LRPAP112140016169070 Two-hybrid
RTN4LRPAP111022116169070 Two-hybrid
RANBP2LRPAP111183920936779 Two-hybrid
RANBP2LRPAP111022120936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
LRPAP1rs1800493, rs35603527 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:96829
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5871'