AutismKB 2.0

Annotation Details for TACSTD2


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Basic Information Top
Gene Symbol:TACSTD2 ( EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TROP2 )
Gene Full Name: tumor-associated calcium signal transducer 2
Band: 1p32.1
Quick LinksEntrez ID:4070; OMIM: 137290; Uniprot ID:TACD2_HUMAN; ENSEMBL ID: ENSG00000184292; HGNC ID: 11530
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IBA-extracellular space-
GO:0005634IBA-nucleus-
GO:0005829TAS-cytosol10192395
GO:0005887TAS-integral component of plasma membrane7665234
GO:0009925ISS-basal plasma membrane-
GO:0016020TAS-membrane8382772
GO:0016328ISS-lateral plasma membrane-
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0004872TAS-receptor activity7665234
GO:0005515IPI-protein binding15607035
GO ID Evidence Qualifier GO_term References
GO:0007166TAS-cell surface receptor signaling pathway7665234
GO:0007601IEA-visual perception-
GO:0008283TAS-cell proliferation7665234
GO:0010633ISS-negative regulation of epithelial cell migration-
GO:0050678IEA-regulation of epithelial cell proliferation-
GO:0051497ISS-negative regulation of stress fiber assembly-
GO:0060675IEA-ureteric bud morphogenesis-
GO:0090191ISS-negative regulation of branching involved in ureteric bud morphogenesis-
GO:0098609IBA-cell-cell adhesion-
GO:1900025ISS-negative regulation of substrate adhesion-dependent cell spreading-
GO:1900028ISS-negative regulation of ruffle assembly-
GO:2000146ISS-negative regulation of cell motility-
GO:2000738IBA-positive regulation of stem cell differentiation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
TACSTD2rs232840 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:1861606
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018