AutismKB 2.0

Annotation Details for EPCAM


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Basic Information Top
Gene Symbol:EPCAM ( DIAR5,EGP-2,EGP314,EGP40,ESA,GA733-2,HNPCC8,KS1/4,KSA,M4S1,MIC18,MK-1,TACSTD1,TROP1 )
Gene Full Name: epithelial cell adhesion molecule
Band: 2p21
Quick LinksEntrez ID:4072; OMIM: 185535; Uniprot ID:EPCAM_HUMAN; ENSEMBL ID: ENSG00000119888; HGNC ID: 11529
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane15195135
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0005923IDA-bicellular tight junction16054130
GO:0009986IEA-cell surface-
GO:0016323IDA-basolateral plasma membrane18025791
GO:0016324IDA-apical plasma membrane18025791
GO:0016328IDA-lateral plasma membrane16054130
GO:0070062IDA-extracellular exosome11487543
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16054130
GO:0032403IDA-protein complex binding19136966
GO:0098641IBA-cadherin binding involved in cell-cell adhesion-
GO ID Evidence Qualifier GO_term References
GO:0001657IEA-ureteric bud development-
GO:0008284IDA-positive regulation of cell proliferation15195135
GO:0023019IMP-signal transduction involved in regulation of gene expression19136966
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter15195135
GO:0048863IMP-stem cell differentiation19785009
GO:0050900TAS-leukocyte migration-
GO:0098742IEA-cell-cell adhesion via plasma-membrane adhesion molecules-
GO:2000048IDA-negative regulation of cell-cell adhesion mediated by cadherin9382878
GO:2000147IEA-positive regulation of cell motility-
GO:2000648IMP-positive regulation of stem cell proliferation19785009
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EPCAMEPCAM11025011058587 Co-purification
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106653
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2209'