Annotation Details for SMAD5


Gene Symbol: | SMAD5 ( DKFZp781C1895,DKFZp781O1323,Dwfc,JV5-1,MADH5 ) |
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Gene Full Name: | SMAD family member 5 |
Band: | 5q31.1 |
Quick Links | Entrez ID:4090; OMIM: 603110; Uniprot ID:SMAD5_HUMAN; ENSEMBL ID: ENSG00000113658; HGNC ID: 6771 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005622 | NAS | - | intracellular | 9759503 |
GO:0005634 | ISS | - | nucleus | - |
GO:0005634 | NAS | - | nucleus | 9759503 |
GO:0005634 | TAS | - | nucleus | 19018011 |
GO:0005654 | IDA | - | nucleoplasm | - |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005667 | IEA | - | transcription factor complex | - |
GO:0005737 | ISS | - | cytoplasm | - |
GO:0005829 | IDA | - | cytosol | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0016021 | NAS | - | integral component of membrane | 10708949 |
GO:0043234 | IDA | - | protein complex | 23610558 |
GO:0071141 | NAS | - | SMAD protein complex | 14687659 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000979 | IEA | - | RNA polymerase II core promoter sequence-specific DNA binding | - |
GO:0003700 | IEA | - | transcription factor activity, sequence-specific DNA binding | - |
GO:0005057 | NAS | - | signal transducer activity, downstream of receptor | 8673135 |
GO:0005515 | IPI | - | protein binding | 15647271 |
GO:0017151 | IPI | - | DEAD/H-box RNA helicase binding | 18548003 |
GO:0030618 | TAS | - | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | 19018011 |
GO:0031625 | IPI | - | ubiquitin protein ligase binding | 11278251 |
GO:0046872 | IEA | - | metal ion binding | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0001657 | IEA | - | ureteric bud development | - |
GO:0001880 | IEA | - | Mullerian duct regression | - |
GO:0002051 | IEA | - | osteoblast fate commitment | - |
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0006468 | IEA | - | protein phosphorylation | - |
GO:0007165 | NAS | - | signal transduction | 9759503 |
GO:0007179 | NAS | - | transforming growth factor beta receptor signaling pathway | 10708948 |
GO:0007281 | IEA | - | germ cell development | - |
GO:0009880 | ISS | - | embryonic pattern specification | - |
GO:0030218 | IEA | - | erythrocyte differentiation | - |
GO:0030509 | ISS | - | BMP signaling pathway | - |
GO:0030509 | TAS | - | BMP signaling pathway | 19018011 |
GO:0045669 | IEA | - | positive regulation of osteoblast differentiation | - |
GO:0045893 | NAS | - | positive regulation of transcription, DNA-templated | 10708949 |
GO:0051216 | IEA | - | cartilage development | - |
GO:0060048 | IEA | - | cardiac muscle contraction | - |
GO:0060348 | IEA | - | bone development | - |
GO:0060395 | ISS | - | SMAD protein signal transduction | - |
GO:0060395 | NAS | - | SMAD protein signal transduction | 14687659 |
GO:0071407 | IEA | - | cellular response to organic cyclic compound | - |
GO:1901522 | ISS | - | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | - |
GO:1901522 | TAS | - | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | 14687659 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
SMAD5 | ACVR1 | 110265 | 9748228 10652350 | Affinity Capture-Western |
SMAD5 | ACVR1 | 106605 | 9748228 10652350 | Affinity Capture-Western |
SMAD5 | RUNX2 | 110265 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX2 | 107308 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX1 | 110265 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX1 | 107309 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX3 | 110265 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX3 | 107312 | 10531362 | Affinity Capture-Western |
SMAD5 | EP300 | 108347 | 16613856 | Affinity Capture-Western |
SMAD5 | EP300 | 110265 | 16613856 | Affinity Capture-Western |
SMAD5 | KAT2A | 110265 | 15009097 | Affinity Capture-Western |
SMAD5 | KAT2A | 108918 | 15009097 | Affinity Capture-Western |
SMAD5 | HDAC1 | 109315 | 14699069 | Affinity Capture-Western |
SMAD5 | HDAC1 | 110265 | 14699069 | Affinity Capture-Western |
SMAD5 | SMAD4 | 110265 | 10531362 | Affinity Capture-Western |
SMAD5 | SMAD4 | 110264 | 10531362 | Affinity Capture-Western |
TOB1 | SMAD5 | 115443 | 11163184 | Affinity Capture-Western |
TOB1 | SMAD5 | 110265 | 11163184 | Affinity Capture-Western |
SKI | SMAD5 | 110265 | 14699069 | Affinity Capture-Western |
SKI | SMAD5 | 112388 | 14699069 | Affinity Capture-Western |
SUV39H1 | SMAD5 | 110265 | 15107829 | Affinity Capture-Western |
SUV39H1 | SMAD5 | 112706 | 15107829 | Affinity Capture-Western |
SUV39H2 | SMAD5 | 110265 | 15107829 | Affinity Capture-Western |
SUV39H2 | SMAD5 | 122838 | 15107829 | Affinity Capture-Western |
WWP1 | SMAD5 | 116243 | 15221015 | Affinity Capture-Western |
WWP1 | SMAD5 | 110265 | 15221015 | Affinity Capture-Western |
SMURF1 | SMAD5 | 121411 | 15221015 18641638 | Affinity Capture-Western |
SMURF1 | SMAD5 | 110265 | 15221015 18641638 | Affinity Capture-Western |
SMURF2 | SMAD5 | 122265 | 15221015 | Affinity Capture-Western |
SMURF2 | SMAD5 | 110265 | 15221015 | Affinity Capture-Western |
HMGA2 | SMAD5 | 113763 | 18425117 | Affinity Capture-Western |
HMGA2 | SMAD5 | 110265 | 18425117 | Affinity Capture-Western |
PLEKHO1 | SMAD5 | 119355 | 18641638 | Affinity Capture-Western; Reconstituted Complex |
PLEKHO1 | SMAD5 | 110265 | 18641638 | Affinity Capture-Western; Reconstituted Complex |
No data |
No data |
- MGI ID: MGI:1328787
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-990603-9