AutismKB 2.0

Annotation Details for ACCN2


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Basic Information Top
Gene Symbol:ACCN2 ( ASIC,ASIC1,ASIC1A,BNaC2,hBNaC2 )
Gene Full Name: amiloride-sensitive cation channel 2, neuronal
Band: 12q12
Quick LinksEntrez ID:41; OMIM: 602866; Uniprot ID:ACCN2_HUMAN; ENSEMBL ID: ENSG00000110881; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IDA-Golgi apparatus-
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887IMP-integral component of plasma membrane22760635
GO:0005887ISS-integral component of plasma membrane-
GO:0009986IEA-cell surface-
GO:0045202IEA-synapse-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11802773
GO:0015280TAS-ligand-gated sodium channel activity9062189
GO:0022839IEA-ion gated channel activity-
GO:0044736IDA-acid-sensing ion channel activity22760635
GO:0044736ISS-acid-sensing ion channel activity-
GO:0044736TAS-acid-sensing ion channel activity-
GO ID Evidence Qualifier GO_term References
GO:0006810TAS-transport9037075
GO:0006814NAS-sodium ion transport9037075
GO:0007165TAS-signal transduction9037075
GO:0007613IEA-memory-
GO:0008306IEA-associative learning-
GO:0009268TAS-response to pH9062189
GO:0010447IEA-response to acidic pH-
GO:0034220TAS-ion transmembrane transport-
GO:0035725IDA-sodium ion transmembrane transport22760635
GO:0035725ISS-sodium ion transmembrane transport-
GO:0042391IEA-regulation of membrane potential-
GO:0046929IEA-negative regulation of neurotransmitter secretion-
GO:0050915IMP-sensory perception of sour taste19812697
GO:0070207ISS-protein homotrimerization-
GO:0070588IEA-calcium ion transmembrane transport-
GO:0071467IDA-cellular response to pH22760635
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PICK1ACCN210655911802773 12578970 Affinity Capture-Western; Two-hybrid
PICK1ACCN211484911802773 12578970 Affinity Capture-Western; Two-hybrid
PRKACAACCN211155312578970 Biochemical Activity
PRKACAACCN210655912578970 Biochemical Activity
STOML1ACCN210655915471860 Affinity Capture-Western
STOML1ACCN211479615471860 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1194915
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040513-1'