AutismKB 2.0

Annotation Details for MAOB


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Basic Information Top
Gene Symbol:MAOB ( MGC26382 )
Gene Full Name: monoamine oxidase B
Band: Xp11.3
Quick LinksEntrez ID:4129; OMIM: 309860; Uniprot ID:AOFB_HUMAN; ENSEMBL ID: ENSG00000069535; HGNC ID: 6834
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion20833797
GO:0005740TAS-mitochondrial envelope7063850
GO:0005741TAS-mitochondrial outer membrane24252804
GO:0005743IEA-mitochondrial inner membrane-
GO:0016021IEA-integral component of membrane-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0008131TAS-primary amine oxidase activity-
GO:0009055TAS-electron carrier activity8602220
GO:0042803IEA-protein homodimerization activity-
GO:0050660IEA-flavin adenine dinucleotide binding-
GO ID Evidence Qualifier GO_term References
GO:0009636IEA-response to toxic substance-
GO:0010044IEA-response to aluminum ion-
GO:0010269IEA-response to selenium ion-
GO:0014063IEA-negative regulation of serotonin secretion-
GO:0021762IEP-substantia nigra development22926577
GO:0032496IEA-response to lipopolysaccharide-
GO:0042135IEA-neurotransmitter catabolic process-
GO:0042420TAS-dopamine catabolic process24252804
GO:0042493IEA-response to drug-
GO:0045471IEA-response to ethanol-
GO:0045964IEA-positive regulation of dopamine metabolic process-
GO:0050665NAS-hydrogen peroxide biosynthetic process24252804
GO:0051412IEA-response to corticosterone-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBCMAOB11030216455660 Affinity Capture-Western
UBCMAOB11316416455660 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
MAOBMAOB_R127G, rs1040398, rs1181252, rs1183035, rs1799836, rs2283729, rs3027452, rs4824562, rs71661031 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
MAOBMAOB_2bpSTR, MAOB_2bpSTR-intra, MAOB_2bpSTR-up, MAOB_MaeIII, rs1181252, rs1183035, rs12851487, rs1799836, rs2311013, rs3027448, rs3027450, rs5905512, rs6651806 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:96916
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018