AutismKB 2.0

Annotation Details for MAP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MAP2 ( DKFZp686I2148,MAP2A,MAP2B,MAP2C )
Gene Full Name: microtubule-associated protein 2
Band: 2q34
Quick LinksEntrez ID:4133; OMIM: 157130; Uniprot ID:MAP2_HUMAN; ENSEMBL ID: ENSG00000078018; HGNC ID: 6839
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005730IDA-nucleolus-
GO:0005829IDA-cytosol-
GO:0005874IEA-microtubule-
GO:0005875TAS-microtubule associated complex9588626
GO:0014069IEA-postsynaptic density-
GO:0030425ISS-dendrite-
GO:0034399IEA-nuclear periphery-
GO:0043005IBA-neuron projection-
GO:0043025IEA-neuronal cell body-
GO:0043198IEA-dendritic shaft-
GO:0097442IEA-CA3 pyramidal cell dendrite-
GO ID Evidence Qualifier GO_term References
GO:0002162IPI-dystroglycan binding18341635
GO:0005198NAS-structural molecule activity9588626
GO:0005515IPI-protein binding20195357
GO:0005516IEA-calmodulin binding-
GO:0008017IBA-microtubule binding-
GO ID Evidence Qualifier GO_term References
GO:0000226IBA-microtubule cytoskeleton organization-
GO:0001578IEA-microtubule bundle formation-
GO:0007409IEA-axonogenesis-
GO:0021954IEP-central nervous system neuron development20846339
GO:0030010IEA-establishment of cell polarity-
GO:0031175IEP-neuron projection development20846339
GO:0048813IEP-dendrite morphogenesis20846339
GO:0050770IEA-regulation of axonogenesis-
GO:0071310IEA-cellular response to organic substance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAP2FYN10881011546790 Affinity Capture-Western
MAP2FYN11030511546790 Affinity Capture-Western
MAP2GRB211030510781592 11546790 Reconstituted Complex
MAP2GRB210914210781592 11546790 Reconstituted Complex
NEFLMAP21103051902666 Reconstituted Complex
NEFLMAP21108221902666 Reconstituted Complex
PLECMAP21103053027087 Reconstituted Complex
PLECMAP21113553027087 Reconstituted Complex
MAP2MAP211030510527895 Reconstituted Complex
SRCMAP211030510781592 Reconstituted Complex
SRCMAP211259210781592 Reconstituted Complex
MYO7AMAP211030511171103 Affinity Capture-Western; Reconstituted Complex
MYO7AMAP211073111171103 Affinity Capture-Western; Reconstituted Complex
MARK4MAP211030514594945 Biochemical Activity
MARK4MAP212176014594945 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97175
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved