AutismKB 2.0

Annotation Details for MATK


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MATK ( CHK,CTK,DKFZp434N1212,HHYLTK,HYL,HYLTK,Lsk,MGC1708,MGC2101 )
Gene Full Name: megakaryocyte-associated tyrosine kinase
Band: 19p13.3
Quick LinksEntrez ID:4145; OMIM: 600038; Uniprot ID:MATK_HUMAN; ENSEMBL ID: ENSG00000007264; HGNC ID: 6906
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0031234IBA-extrinsic component of cytoplasmic side of plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0004713TAS-protein tyrosine kinase activity7530249
GO:0004715IBA-non-membrane spanning protein tyrosine kinase activity-
GO:0005102IBA-receptor binding-
GO:0005515IPI-protein binding12122014
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation7530249
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007498TAS-mesoderm development8288563
GO:0008283TAS-cell proliferation8288563
GO:0008284TAS-positive regulation of cell proliferation8999872
GO:0030154IBA-cell differentiation-
GO:0038083IBA-peptidyl-tyrosine autophosphorylation-
GO:0038128TAS-ERBB2 signaling pathway-
GO:0045087IBA-innate immune response-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MATKCD361103159171348 Affinity Capture-Western
MATKCD361073869171348 Affinity Capture-Western
MATKEWSR110843116189514 Two-hybrid
MATKEWSR111031516189514 Two-hybrid
MATKKIT1100157536744 9038210 Reconstituted Complex
MATKKIT1103157536744 9038210 Reconstituted Complex
SRCMATK1125927530249 Biochemical Activity
SRCMATK1103157530249 Biochemical Activity
PXNMATK11178710080957 Affinity Capture-Western
PXNMATK11031510080957 Affinity Capture-Western
NTRK1MATK11096910329710 Affinity Capture-Western; Far Western
NTRK1MATK11031510329710 Affinity Capture-Western; Far Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99259
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070705-183'