AutismKB 2.0

Annotation Details for MBP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MBP ( MGC99675 )
Gene Full Name: myelin basic protein
Band: 18q23
Quick LinksEntrez ID:4155; OMIM: 159430; Uniprot ID:MBP_HUMAN; ENSEMBL ID: ENSG00000197971; HGNC ID: 6925
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IDA-intracellular22524708
GO:0005634IEA-nucleus-
GO:0005886IEA-plasma membrane-
GO:0033269IEA-internode region of axon-
GO:0043025IEA-neuronal cell body-
GO:0043209IDA-myelin sheath19855925
GO:0043234IDA-protein complex19855925
GO ID Evidence Qualifier GO_term References
GO:0002020IEA-protease binding-
GO:0005515IPI-protein binding25416956
GO:0005516IPI-calmodulin binding19855925
GO:0019911IEA-structural constituent of myelin sheath-
GO ID Evidence Qualifier GO_term References
GO:0000165IDA-MAPK cascade22524708
GO:0006955TAS-immune response7504278
GO:0007268TAS-chemical synaptic transmission2434243
GO:0007417TAS-central nervous system development2434243
GO:0007605IEA-sensory perception of sound-
GO:0008366TAS-axon ensheathment2434243
GO:0009636IEA-response to toxic substance-
GO:0021762IEP-substantia nigra development22926577
GO:0034115IDA-negative regulation of heterotypic cell-cell adhesion22524708
GO:0035633IDA-maintenance of permeability of blood-brain barrier22524708
GO:0042552IEA-myelination-
GO:0061024IEA-membrane organization-
GO:1904209IDA-positive regulation of chemokine (C-C motif) ligand 2 secretion22524708
GO:1904685IDA-positive regulation of metalloendopeptidase activity22524708
GO:2000778IDA-positive regulation of interleukin-6 secretion22524708
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MBPHLA-DRA1103259782128 Co-crystal Structure
MBPHLA-DRA1093679782128 Co-crystal Structure
PLP1MBP1103252467009 6083474 Co-purification; Reconstituted Complex
PLP1MBP1113682467009 6083474 Co-purification; Reconstituted Complex
STK39MBP11032510980603 Biochemical Activity
STK39MBP11815910980603 Biochemical Activity
PRMT5MBP11032511152681 Biochemical Activity
PRMT5MBP11568811152681 Biochemical Activity
TRPM7MBP12017714594813 Biochemical Activity
TRPM7MBP11032514594813 Biochemical Activity
TSSK6MBP11032515870294 Biochemical Activity
TSSK6MBP12383515870294 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
MBPrs10514234, rs2282557, rs3794835, rs3794851, rs470131, rs470826, rs4890875, rs4890876, rs509620 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:96925
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030128-2'