AutismKB 2.0

Annotation Details for MCC


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Basic Information Top
Gene Symbol:MCC ( DKFZp762O1615,FLJ38893,FLJ46755,MCC1 )
Gene Full Name: mutated in colorectal cancers
Band: 5q22.2
Quick LinksEntrez ID:4163; OMIM: 159350; Uniprot ID:CRCM_HUMAN; ENSEMBL ID: ENSG00000171444; HGNC ID: 6935
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus18591935
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm18591935
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane19555689
GO:0030027IEA-lamellipodium-
GO ID Evidence Qualifier GO_term References
GO:0004872TAS-receptor activity1848370
GO:0005515IPI-protein binding18591935
GO ID Evidence Qualifier GO_term References
GO:0007165TAS-signal transduction1848370
GO:0010633IMP-negative regulation of epithelial cell migration19555689
GO:0016055IEA-Wnt signaling pathway-
GO:0045184IDA-establishment of protein localization18591935
GO:0050680IDA-negative regulation of epithelial cell proliferation18591935
GO:0090090IDA-negative regulation of canonical Wnt signaling pathway18591935
GO:0090090IMP-negative regulation of canonical Wnt signaling pathway24824780
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MCCCBR111033317353931 Affinity Capture-MS
MCCCBR110731917353931 Affinity Capture-MS
MCCCLTC11033317353931 Affinity Capture-MS
MCCCLTC10762317353931 Affinity Capture-MS
MCCCSNK1D11033317353931 Affinity Capture-MS
MCCCSNK1D10783717353931 Affinity Capture-MS
MCCCSNK1E11033317353931 Affinity Capture-MS
MCCCSNK1E10783817353931 Affinity Capture-MS
MCCDFFA11033317353931 Affinity Capture-MS
MCCDFFA10804017353931 Affinity Capture-MS
MCCEPRS11033317353931 Affinity Capture-MS
MCCEPRS10837217353931 Affinity Capture-MS
MCCHPRT110948817353931 Affinity Capture-MS
MCCHPRT111033317353931 Affinity Capture-MS
MCCIARS11033317353931 Affinity Capture-MS
MCCIARS10960517353931 Affinity Capture-MS
MCCKRT1811007317353931 Affinity Capture-MS
MCCKRT1811033317353931 Affinity Capture-MS
MCCLTA4H11022617353931 Affinity Capture-MS
MCCLTA4H11033317353931 Affinity Capture-MS
MCCMARS11031117353931 Affinity Capture-MS
MCCMARS11033317353931 Affinity Capture-MS
PSME3MCC11549217353931 Affinity Capture-MS
PSME3MCC11033317353931 Affinity Capture-MS
PAICSMCC11585217353931 Affinity Capture-MS
PAICSMCC11033317353931 Affinity Capture-MS
PDCD10MCC11640017353931 Affinity Capture-MS
PDCD10MCC11033317353931 Affinity Capture-MS
SNRNP200MCC11666117353931 Affinity Capture-MS
SNRNP200MCC11033317353931 Affinity Capture-MS
STRN4MCC11894117353931 Affinity Capture-MS
STRN4MCC11033317353931 Affinity Capture-MS
STRN3MCC11899917353931 Affinity Capture-MS
STRN3MCC11033317353931 Affinity Capture-MS
MTHFD1MCC11062217353931 Affinity Capture-MS
MTHFD1MCC11033317353931 Affinity Capture-MS
MYH10MCC11071317353931 Affinity Capture-MS
MYH10MCC11033317353931 Affinity Capture-MS
PFASMCC11122117353931 Affinity Capture-MS
PFASMCC11033317353931 Affinity Capture-MS
PFKPMCC11123517353931 Affinity Capture-MS
PFKPMCC11033317353931 Affinity Capture-MS
PPP2R1AMCC11033317353931 Affinity Capture-MS
PPP2R1AMCC11151017353931 Affinity Capture-MS
VPS35MCC12085517353931 Affinity Capture-MS
VPS35MCC11033317353931 Affinity Capture-MS
PSMD2MCC11168117353931 Affinity Capture-MS
PSMD2MCC11033317353931 Affinity Capture-MS
STRNMCC11267417353931 Affinity Capture-MS
STRNMCC11033317353931 Affinity Capture-MS
TARSMCC11276017353931 Affinity Capture-MS
TARSMCC11033317353931 Affinity Capture-MS
TPM3MCC11302317353931 Affinity Capture-MS
TPM3MCC11033317353931 Affinity Capture-MS
VCPMCC11325817353931 Affinity Capture-MS
VCPMCC11033317353931 Affinity Capture-MS
VDAC1MCC11325917353931 Affinity Capture-MS
VDAC1MCC11033317353931 Affinity Capture-MS
VHLMCC11326917353931 Affinity Capture-MS
VHLMCC11033317353931 Affinity Capture-MS
EZRMCC11327117353931 Affinity Capture-MS
EZRMCC11033317353931 Affinity Capture-MS
STK24MCC11401117353931 Affinity Capture-MS
STK24MCC11033317353931 Affinity Capture-MS
FAM40AMCC12449717353931 Affinity Capture-MS
FAM40AMCC11033317353931 Affinity Capture-MS
EIF3AMCC11421017353931 Affinity Capture-MS
EIF3AMCC11033317353931 Affinity Capture-MS
CCNA1MCC11441717353931 Affinity Capture-MS
CCNA1MCC11033317353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96930
  • Data Attributes: MGI curated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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