AutismKB 2.0

Annotation Details for MCM2


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Basic Information Top
Gene Symbol:MCM2 ( BM28,CCNL1,CDCL1,D3S3194,KIAA0030,MGC10606,MITOTIN,cdc19 )
Gene Full Name: minichromosome maintenance complex component 2
Band: 3q21.3
Quick LinksEntrez ID:4171; OMIM: 116945; Uniprot ID:MCM2_HUMAN; ENSEMBL ID: ENSG00000073111; HGNC ID: 6944
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000784IDA-nuclear chromosome, telomeric region19135898
GO:0000785IDA-chromatin16899510
GO:0005634IDA-nucleus16899510
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005664IEA-nuclear origin of replication recognition complex-
GO:0005730IDANOTnucleolus21383955
GO:0005737IDA-cytoplasm26196677
GO:0005829IDA-cytosol-
GO:0015630IDA-microtubule cytoskeleton-
GO:0042555IDA-MCM complex17296731
GO ID Evidence Qualifier GO_term References
GO:0003677TAS-DNA binding8175912
GO:0003678IEA-DNA helicase activity-
GO:0003688IEA-DNA replication origin binding-
GO:0005515IPI-protein binding11095689
GO:0005524IEA-ATP binding-
GO:0019899IEA-enzyme binding-
GO:0042393IEA-histone binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000082TAS-G1/S transition of mitotic cell cycle-
GO:0006260TAS-DNA replication-
GO:0006268IEA-DNA unwinding involved in DNA replication-
GO:0006270IMP-DNA replication initiation16899510
GO:0006334IEA-nucleosome assembly-
GO:0006915IMP-apoptotic process26196677
GO:0071353IEA-cellular response to interleukin-4-
GO:0090102IMP-cochlea development26196677
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MCM2AIRE10682320085707 Affinity Capture-MS
MCM2AIRE11033920085707 Affinity Capture-MS
MCM2ATM11033915210935 Biochemical Activity
MCM2ATM10696215210935 Biochemical Activity
MCM2ATR10702715210935 Biochemical Activity
MCM2ATR11033915210935 Biochemical Activity
MCM2CCNC10733312392551 Reconstituted Complex
MCM2CCNC11033912392551 Reconstituted Complex
MCM2PHC210823416169070 Two-hybrid
MCM2PHC211033916169070 Two-hybrid
MCM2EMD11033917620012 Affinity Capture-MS
MCM2EMD10832517620012 Affinity Capture-MS
MCM4MCM21103418798650 10567526 12614612 12694531 16902406 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM4MCM21103398798650 10567526 12614612 12694531 16902406 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM7MCM21103449099751 10567526 12207017 12614612 12694531 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM7MCM21103399099751 10567526 12207017 12614612 12694531 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM6MCM211034310567526 12207017 12614612 12694531 16189514 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM6MCM211033910567526 12207017 12614612 12694531 16189514 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM5MCM211034211248027 12614612 Affinity Capture-Western; Two-hybrid
MCM5MCM211033911248027 12614612 Affinity Capture-Western; Two-hybrid
TBPMCM211277112392551 Reconstituted Complex
TBPMCM211033912392551 Reconstituted Complex
TCEA2MCM211278112392551 Reconstituted Complex
TCEA2MCM211033912392551 Reconstituted Complex
ORC2MCM211104112614612 Affinity Capture-Western; Two-hybrid
ORC2MCM211033912614612 Affinity Capture-Western; Two-hybrid
CDC7MCM211391412614612 16826239 Biochemical Activity; Two-hybrid
CDC7MCM211033912614612 16826239 Biochemical Activity; Two-hybrid
DBF4MCM211612912614612 Two-hybrid
DBF4MCM211033912614612 Two-hybrid
MCM2MCM211033912614612 Two-hybrid
MCM3MCM211033912614612 Two-hybrid
MCM3MCM211034012614612 Two-hybrid
ORC1MCM211104012614612 Two-hybrid
ORC1MCM211033912614612 Two-hybrid
ORC4MCM211104212614612 Two-hybrid
ORC4MCM211033912614612 Two-hybrid
ORC5MCM211104312614612 Two-hybrid
ORC5MCM211033912614612 Two-hybrid
RPA1MCM211033912614612 Two-hybrid
RPA1MCM211203712614612 Two-hybrid
RPA2MCM211203812614612 Two-hybrid
RPA2MCM211033912614612 Two-hybrid
RPA3MCM211203912614612 Two-hybrid
RPA3MCM211033912614612 Two-hybrid
AKAP8MCM211556112740381 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AKAP8MCM211033912740381 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GNB5MCM211592016169070 Two-hybrid
GNB5MCM211033916169070 Two-hybrid
MOBKL3MCM211736916169070 Two-hybrid
MOBKL3MCM211033916169070 Two-hybrid
MPP3MCM211049616169070 Two-hybrid
MPP3MCM211033916169070 Two-hybrid
RPS4XMCM211210516169070 Two-hybrid
RPS4XMCM211033916169070 Two-hybrid
MGMTMCM211041116226712 Affinity Capture-Western
MGMTMCM211033916226712 Affinity Capture-Western
ING5MCM212401616387653 Affinity Capture-Western
ING5MCM211033916387653 Affinity Capture-Western
MYST2MCM211631516428461 Biochemical Activity
MYST2MCM211033916428461 Biochemical Activity
SSRP1MCM211262716902406 Affinity Capture-Western
SSRP1MCM211033916902406 Affinity Capture-Western
MCPH1MCM212277619525936 Reconstituted Complex
MCPH1MCM211033919525936 Reconstituted Complex
BRCC3MCM212259919615732 Affinity Capture-MS
BRCC3MCM211033919615732 Affinity Capture-MS
HIST1H4AMCM211395519862764 Affinity Capture-MS; Affinity Capture-Western
HIST1H4AMCM211033919862764 Affinity Capture-MS; Affinity Capture-Western
PRKAG1MCM211155820562859 Affinity Capture-MS
PRKAG1MCM211033920562859 Affinity Capture-MS
DDA1MCM212248520562859 Affinity Capture-MS
DDA1MCM211033920562859 Affinity Capture-MS
UBA5MCM212296420562859 Affinity Capture-MS
UBA5MCM211033920562859 Affinity Capture-MS
CCL2MCM211225121383955 Affinity Capture-Western
CCL2MCM211033921383955 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105380
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020419-24'