AutismKB 2.0

Annotation Details for MCM4


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Basic Information Top
Gene Symbol:MCM4 ( CDC21,CDC54,MGC33310,P1-CDC21,hCdc21 )
Gene Full Name: minichromosome maintenance complex component 4
Band: 8q11.21
Quick LinksEntrez ID:4173; OMIM: 602638; Uniprot ID:MCM4_HUMAN; ENSEMBL ID: ENSG00000104738; HGNC ID: 6947
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000784IDA-nuclear chromosome, telomeric region19135898
GO:0005634NAS-nucleus8265339
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016020IDA-membrane19946888
GO:0042555IDA-MCM complex17296731
GO ID Evidence Qualifier GO_term References
GO:0003697IEA-single-stranded DNA binding-
GO:0004003IDAcontributes_toATP-dependent DNA helicase activity9305914
GO:0005515IPI-protein binding12364596
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0000082TAS-G1/S transition of mitotic cell cycle-
GO:0006260NAS-DNA replication9465298
GO:0006260TAS-DNA replication-
GO:0006268IEA-DNA unwinding involved in DNA replication-
GO:0006270IEA-DNA replication initiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MCM4CDK210745210748114 Biochemical Activity
MCM4CDK211034110748114 Biochemical Activity
MCM4EMD10832517620012 Affinity Capture-MS
MCM4EMD11034117620012 Affinity Capture-MS
MCM4TLX210943620211142 Two-hybrid
MCM4TLX211034120211142 Two-hybrid
MCM4MCM21103418798650 10567526 12614612 12694531 16902406 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM4MCM21103398798650 10567526 12614612 12694531 16902406 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM7MCM41103418798650 9099751 12207017 12694531 Affinity Capture-Western; Reconstituted Complex
MCM7MCM41103448798650 9099751 12207017 12694531 Affinity Capture-Western; Reconstituted Complex
MCM6MCM41103418798650 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM6MCM41103438798650 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM5MCM411034211248027 Affinity Capture-Western
MCM5MCM411034111248027 Affinity Capture-Western
DBF4MCM411034112614612 Two-hybrid
DBF4MCM411612912614612 Two-hybrid
ORC6MCM411712912614612 Two-hybrid
ORC6MCM411034112614612 Two-hybrid
ORC3MCM411713012614612 Two-hybrid
ORC3MCM411034112614612 Two-hybrid
MCM4MCM411034112614612 Two-hybrid
ORC1MCM411034112614612 Two-hybrid
ORC1MCM411104012614612 Two-hybrid
ORC2MCM411034112614612 Two-hybrid
ORC2MCM411104112614612 Two-hybrid
ORC4MCM411034112614612 Two-hybrid
ORC4MCM411104212614612 Two-hybrid
ORC5MCM411104312614612 Two-hybrid
ORC5MCM411034112614612 Two-hybrid
RPA1MCM411034112614612 Two-hybrid
RPA1MCM411203712614612 Two-hybrid
RPA2MCM411034112614612 Two-hybrid
RPA2MCM411203812614612 Two-hybrid
CDC7MCM411034112614612 Two-hybrid
CDC7MCM411391412614612 Two-hybrid
MCM8MCM412410912771218 Affinity Capture-Western
MCM8MCM411034112771218 Affinity Capture-Western
ING5MCM412401616387653 Affinity Capture-Western
ING5MCM411034116387653 Affinity Capture-Western
CDC45MCM411034116902406 Affinity Capture-Western
CDC45MCM411391516902406 Affinity Capture-Western
SUPT16HMCM411034116902406 Affinity Capture-Western; Reconstituted Complex
SUPT16HMCM411636716902406 Affinity Capture-Western; Reconstituted Complex
SSRP1MCM411034116902406 Affinity Capture-Western; Reconstituted Complex
SSRP1MCM411262716902406 Affinity Capture-Western; Reconstituted Complex
CDT1MCM412355518162579 Affinity Capture-MS; Reconstituted Complex
CDT1MCM411034118162579 Affinity Capture-MS; Reconstituted Complex
USP7MCM411034119615732 Affinity Capture-MS
USP7MCM411362219615732 Affinity Capture-MS
HIST1H4AMCM411034119862764 Affinity Capture-MS; Affinity Capture-Western
HIST1H4AMCM411395519862764 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103199
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9544'