AutismKB 2.0

Annotation Details for MCM6


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Basic Information Top
Gene Symbol:MCM6 ( MCG40308,Mis5,P105MCM )
Gene Full Name: minichromosome maintenance complex component 6
Band: 2q21.3
Quick LinksEntrez ID:4175; OMIM: 601806; Uniprot ID:MCM6_HUMAN; ENSEMBL ID: ENSG00000076003; HGNC ID: 6949
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000784IDA-nuclear chromosome, telomeric region19135898
GO:0005634IDA-nucleus16899510
GO:0005634NAS-nucleus9286856
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0042555IDA-MCM complex17296731
GO ID Evidence Qualifier GO_term References
GO:0003697IEA-single-stranded DNA binding-
GO:0004003IDAcontributes_toATP-dependent DNA helicase activity9305914
GO:0005515IPI-protein binding11095689
GO:0005524NAS-ATP binding9286856
GO:0042802IPI-identical protein binding15232106
GO ID Evidence Qualifier GO_term References
GO:0000082TAS-G1/S transition of mitotic cell cycle-
GO:0006260NAS-DNA replication9286856
GO:0006260TAS-DNA replication-
GO:0006268IEA-DNA unwinding involved in DNA replication-
GO:0006270IEA-DNA replication initiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MCM6AIRE10682320085707 Affinity Capture-MS
MCM6AIRE11034320085707 Affinity Capture-MS
MCM6EMD11034317620012 Affinity Capture-MS
MCM6EMD10832517620012 Affinity Capture-MS
MCM6MCM211034310567526 12207017 12614612 12694531 16189514 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM6MCM211033910567526 12207017 12614612 12694531 16189514 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM6MCM41103418798650 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM6MCM41103438798650 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM6MCM511034211248027 Affinity Capture-Western
MCM6MCM511034311248027 Affinity Capture-Western
MCM7MCM61103439099751 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM7MCM61103449099751 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM6MCM611034312614612 12694531 16189514 Reconstituted Complex; Two-hybrid
ORC1MCM611104012614612 Two-hybrid
ORC1MCM611034312614612 Two-hybrid
ORC2MCM611104112614612 Two-hybrid
ORC2MCM611034312614612 Two-hybrid
ORC4MCM611034312614612 Two-hybrid
ORC4MCM611104212614612 Two-hybrid
RPA1MCM611034312614612 Two-hybrid
RPA1MCM611203712614612 Two-hybrid
CDC45MCM611034312614612 Two-hybrid
CDC45MCM611391512614612 Two-hybrid
MCM8MCM612410912771218 Affinity Capture-Western
MCM8MCM611034312771218 Affinity Capture-Western
SRRM2MCM611707116159877 Affinity Capture-MS
SRRM2MCM611034316159877 Affinity Capture-MS
ING5MCM612401616189514 16387653 Affinity Capture-Western; Two-hybrid
ING5MCM611034316189514 16387653 Affinity Capture-Western; Two-hybrid
ALS2CR11MCM612735816189514 Two-hybrid
ALS2CR11MCM611034316189514 Two-hybrid
IL1F5MCM611034316189514 Two-hybrid
IL1F5MCM611772816189514 Two-hybrid
MLLT3MCM611044616189514 Two-hybrid
MLLT3MCM611034316189514 Two-hybrid
MCM10MCM612065416189514 Two-hybrid
MCM10MCM611034316189514 Two-hybrid
PSMA1MCM611034316189514 Two-hybrid
PSMA1MCM611165516189514 Two-hybrid
SCNM1MCM612247616189514 Two-hybrid
SCNM1MCM611034316189514 Two-hybrid
SSRP1MCM611034316902406 Affinity Capture-Western
SSRP1MCM611262716902406 Affinity Capture-Western
PMS1MCM611139117148452 Affinity Capture-Western
PMS1MCM611034317148452 Affinity Capture-Western
TAF10MCM611034317643375 Affinity Capture-MS
TAF10MCM611274417643375 Affinity Capture-MS
CDT1MCM611034318162579 18184650 Affinity Capture-MS; Affinity Capture-Western
CDT1MCM612355518162579 18184650 Affinity Capture-MS; Affinity Capture-Western
USP49MCM611034319615732 Affinity Capture-MS
USP49MCM611738219615732 Affinity Capture-MS
TNFAIP3MCM611034319615732 Affinity Capture-MS
TNFAIP3MCM611298319615732 Affinity Capture-MS
USP7MCM611034319615732 Affinity Capture-MS
USP7MCM611362219615732 Affinity Capture-MS
HIST1H4AMCM611395519862764 Affinity Capture-MS; Affinity Capture-Western
HIST1H4AMCM611034319862764 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1298227
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030909-6'