AutismKB 2.0

Annotation Details for MCM7


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Basic Information Top
Gene Symbol:MCM7 ( CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146 )
Gene Full Name: minichromosome maintenance complex component 7
Band: 7q22.1
Quick LinksEntrez ID:4176; OMIM: 600592; Uniprot ID:MCM7_HUMAN; ENSEMBL ID: ENSG00000166508; HGNC ID: 6950
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000784IDA-nuclear chromosome, telomeric region19135898
GO:0000785TAS-chromatin8798650
GO:0005634IDA-nucleus21383955
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005730IDANOTnucleolus21383955
GO:0005829IDA-cytosol-
GO:0016020IDA-membrane19946888
GO:0042555IDA-MCM complex17296731
GO:0042555IMP-MCM complex15538388
GO ID Evidence Qualifier GO_term References
GO:0003677TAScontributes_toDNA binding15538388
GO:0003697IEA-single-stranded DNA binding-
GO:0004003IDAcontributes_toATP-dependent DNA helicase activity9305914
GO:0005515IPI-protein binding9705868
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0000082TAS-G1/S transition of mitotic cell cycle-
GO:0006260TAS-DNA replication-
GO:0006268IEA-DNA unwinding involved in DNA replication-
GO:0006270IEA-DNA replication initiation-
GO:0006974IMP-cellular response to DNA damage stimulus15538388
GO:0008283IEA-cell proliferation-
GO:0042325IMP-regulation of phosphorylation15538388
GO:0042493IEA-response to drug-
GO:0071364IEA-cellular response to epidermal growth factor stimulus-
GO:0071466IEA-cellular response to xenobiotic stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MCM7ATR10702715210935 Affinity Capture-Western
MCM7ATR11034415210935 Affinity Capture-Western
MCM7CCNH11034411056214 Affinity Capture-Western
MCM7CCNH10734211056214 Affinity Capture-Western
MCM7CDC610742610464337 12614612 Affinity Capture-Western; Two-hybrid
MCM7CDC611034410464337 12614612 Affinity Capture-Western; Two-hybrid
MCM7CDK710745711056214 Affinity Capture-Western
MCM7CDK711034411056214 Affinity Capture-Western
MCM7FHL211034410649446 Two-hybrid
MCM7FHL210856510649446 Two-hybrid
MCM7MCM21103449099751 10567526 12207017 12614612 12694531 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM7MCM21103399099751 10567526 12207017 12614612 12694531 Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
MCM7MCM31103449099751 10464337 11779870 12614612 Affinity Capture-Western; Co-fractionation; Two-hybrid
MCM7MCM31103409099751 10464337 11779870 12614612 Affinity Capture-Western; Co-fractionation; Two-hybrid
MCM7MCM41103418798650 9099751 12207017 12694531 Affinity Capture-Western; Reconstituted Complex
MCM7MCM41103448798650 9099751 12207017 12694531 Affinity Capture-Western; Reconstituted Complex
MCM7MCM51103429099751 11248027 12614612 Affinity Capture-Western; Two-hybrid
MCM7MCM51103449099751 11248027 12614612 Affinity Capture-Western; Two-hybrid
MCM7MCM61103439099751 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM7MCM61103449099751 12207017 12614612 12694531 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RB1MCM71118609566894 16912045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RB1MCM71103449566894 16912045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBL1MCM71103449566894 Reconstituted Complex
RBL1MCM71118689566894 Reconstituted Complex
RBL2MCM71118699566894 Reconstituted Complex
RBL2MCM71103449566894 Reconstituted Complex
UBE3AMCM71103449852095 Affinity Capture-Western; Reconstituted Complex
UBE3AMCM71131859852095 Affinity Capture-Western; Reconstituted Complex
CDC45MCM711034410518787 12614612 16912045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CDC45MCM711391510518787 12614612 16912045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MNAT1MCM711034411056214 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MNAT1MCM711047411056214 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MCM10MCM711034411095689 Co-fractionation
MCM10MCM712065411095689 Co-fractionation
MCM7MCM711034412614612 12694531 Reconstituted Complex; Two-hybrid
DBF4MCM711034412614612 Two-hybrid
DBF4MCM711612912614612 Two-hybrid
ORC3MCM711034412614612 Two-hybrid
ORC3MCM711713012614612 Two-hybrid
ORC1MCM711104012614612 Two-hybrid
ORC1MCM711034412614612 Two-hybrid
ORC2MCM711034412614612 Two-hybrid
ORC2MCM711104112614612 Two-hybrid
ORC5MCM711104312614612 Two-hybrid
ORC5MCM711034412614612 Two-hybrid
RPA1MCM711034412614612 Two-hybrid
RPA1MCM711203712614612 Two-hybrid
CDC7MCM711034412614612 Two-hybrid
CDC7MCM711391412614612 Two-hybrid
MCM8MCM712410912771218 Affinity Capture-Western
MCM8MCM711034412771218 Affinity Capture-Western
ATRIPMCM731346315210935 Affinity Capture-Western
ATRIPMCM711034415210935 Affinity Capture-Western
MBIPMCM711961216189514 Two-hybrid
MBIPMCM711034416189514 Two-hybrid
RBM8AMCM711526516189514 Two-hybrid
RBM8AMCM711034416189514 Two-hybrid
SSRP1MCM711034416902406 Affinity Capture-Western
SSRP1MCM711262716902406 Affinity Capture-Western
GIPC1MCM711597817353931 Affinity Capture-MS
GIPC1MCM711034417353931 Affinity Capture-MS
NEK6MCM711034417353931 Affinity Capture-MS
NEK6MCM711600017353931 Affinity Capture-MS
GSTK1MCM713187517353931 Affinity Capture-MS
GSTK1MCM711034417353931 Affinity Capture-MS
MYCMCM711069417353931 Affinity Capture-MS
MYCMCM711034417353931 Affinity Capture-MS
TH1LMCM711957217353931 Affinity Capture-MS
TH1LMCM711034417353931 Affinity Capture-MS
PELOMCM711034417353931 Affinity Capture-MS
PELOMCM711981817353931 Affinity Capture-MS
TRAF6MCM711304117353931 Affinity Capture-MS
TRAF6MCM711034417353931 Affinity Capture-MS
CNOT8MCM711474417353931 Affinity Capture-MS
CNOT8MCM711034417353931 Affinity Capture-MS
CDT1MCM711034418162579 Reconstituted Complex
CDT1MCM712355518162579 Reconstituted Complex
RECQL5MCM711479719270065 Affinity Capture-MS
RECQL5MCM711034419270065 Affinity Capture-MS
SUV420H2MCM712425719486527 Affinity Capture-MS
SUV420H2MCM711034419486527 Affinity Capture-MS
HIST1H4AMCM711034419862764 Affinity Capture-MS; Affinity Capture-Western
HIST1H4AMCM711395519862764 Affinity Capture-MS; Affinity Capture-Western
IKBKGMCM711034420098747 Reconstituted Complex
IKBKGMCM711408920098747 Reconstituted Complex
HIST3H3MCM711389520953179 Affinity Capture-MS
HIST3H3MCM711034420953179 Affinity Capture-MS
CCL2MCM711225121383955 Affinity Capture-Western
CCL2MCM711034421383955 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
RBL1MCM71834009566894 MCM7 interacts with p107.
RB1MCM71833119566894 MCM7 interacts with Rb.
RBL2MCM71834169566894 MCM7 interacts with p130.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1298398
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020419-27'