AutismKB 2.0

Annotation Details for ME1


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Basic Information Top
Gene Symbol:ME1 ( HUMNDME,MES )
Gene Full Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Band: 6q14.2
Quick LinksEntrez ID:4199; OMIM: 154250; Uniprot ID:MAOX_HUMAN; ENSEMBL ID: ENSG00000065833; HGNC ID: 6983
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IBA-mitochondrion-
GO:0005829ISS-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004470IDA-malic enzyme activity7622060
GO:0004470IMP-malic enzyme activity23334421
GO:0004471IEA-malate dehydrogenase (decarboxylating) (NAD+) activity-
GO:0004473IDA-malate dehydrogenase (decarboxylating) (NADP+) activity8187880
GO:0004473ISS-malate dehydrogenase (decarboxylating) (NADP+) activity-
GO:0008948IEA-oxaloacetate decarboxylase activity-
GO:0009055TAS-electron carrier activity7622060
GO:0030145IDA-manganese ion binding7622060
GO:0043531TAS-ADP binding7622060
GO:0050661TAS-NADP binding7622060
GO:0051287TAS-NAD binding7622060
GO ID Evidence Qualifier GO_term References
GO:0005975NAS-carbohydrate metabolic process8187880
GO:0006090IBA-pyruvate metabolic process-
GO:0006108IDA-malate metabolic process7622060
GO:0006741TAS-NADP biosynthetic process8187880
GO:0009725ISS-response to hormone-
GO:0009743TAS-response to carbohydrate8187880
GO:0019216TAS-regulation of lipid metabolic process-
GO:0051262IEA-protein tetramerization-
GO:0055114IEA-oxidation-reduction process-
GO:1902031IMP-regulation of NADP metabolic process23334421
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97043
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061013-438'