AutismKB 2.0

Annotation Details for MEF2D


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Basic Information Top
Gene Symbol:MEF2D ( DKFZp686I1536 )
Gene Full Name: myocyte enhancer factor 2D
Band: 1q22
Quick LinksEntrez ID:4209; OMIM: 600663; Uniprot ID:MEF2D_HUMAN; ENSEMBL ID: ENSG00000116604; HGNC ID: 6997
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus20590529
GO:0005654IDA-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding20590529
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000981IDA-RNA polymerase II transcription factor activity, sequence-specific DNA binding20590529
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding8575763
GO:0005515IPI-protein binding16043483
GO:0033613IPI-activating transcription factor binding20590529
GO:0042803IEA-protein homodimerization activity-
GO:0042826IPI-histone deacetylase binding20590529
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001649IEA-osteoblast differentiation-
GO:0001958IEA-endochondral ossification-
GO:0002062IEA-chondrocyte differentiation-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0006915IEA-apoptotic process-
GO:0007399IEA-nervous system development-
GO:0007512IEP-adult heart development10458488
GO:0007517TAS-muscle organ development8269842
GO:0035914IEA-skeletal muscle cell differentiation-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter20590529
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MEF2DMAPK1411037320936779 Two-hybrid
MEF2DMAPK1410781920936779 Two-hybrid
MEF2DEP30011037310825153 10933397 Affinity Capture-Western
MEF2DEP30010834710825153 10933397 Affinity Capture-Western
MEF2DMEF2A1103738798771 Affinity Capture-Western; Co-localization
MEF2DMEF2A1103698798771 Affinity Capture-Western; Co-localization
MAPK7MEF2D1103739753748 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
MAPK7MEF2D1115849753748 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
HDAC4MEF2D11037310523670 16166628 16356933 17158926 Affinity Capture-Western
HDAC4MEF2D11510610523670 16166628 16356933 17158926 Affinity Capture-Western
CABIN1MEF2D11037310531067 10933397 Affinity Capture-Western; Reconstituted Complex
CABIN1MEF2D11707010531067 10933397 Affinity Capture-Western; Reconstituted Complex
NFATC2MEF2D11037310944115 Affinity Capture-Western; Reconstituted Complex
NFATC2MEF2D11084610944115 Affinity Capture-Western; Reconstituted Complex
YWHAQMEF2D11037311433030 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQMEF2D11616811433030 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SP1MEF2D11037312213324 Affinity Capture-Western; Reconstituted Complex
SP1MEF2D11255012213324 Affinity Capture-Western; Reconstituted Complex
HDAC5MEF2D11037312896970 Affinity Capture-Western
HDAC5MEF2D11533112896970 Affinity Capture-Western
SENP3MEF2D11037315743823 Affinity Capture-Western
SENP3MEF2D11759415743823 Affinity Capture-Western
SUMO1MEF2D11037316166628 Affinity Capture-Western
SUMO1MEF2D11318816166628 Affinity Capture-Western
SUMO2MEF2D11249716356933 Affinity Capture-Western
SUMO2MEF2D11037316356933 Affinity Capture-Western
KAT2BMEF2D11037317158926 Affinity Capture-Western
KAT2BMEF2D11437517158926 Affinity Capture-Western
HDAC3MEF2D11037317158926 Affinity Capture-Western; Biochemical Activity
HDAC3MEF2D11436817158926 Affinity Capture-Western; Biochemical Activity
MEN1MEF2D11038418026121 Affinity Capture-Western
MEN1MEF2D11037318026121 Affinity Capture-Western
RBBP5MEF2D11037318026121 Affinity Capture-Western
RBBP5MEF2D11186418026121 Affinity Capture-Western
MLL2MEF2D11037318026121 Affinity Capture-Western
MLL2MEF2D11375818026121 Affinity Capture-Western
ASH2LMEF2D11037318026121 Affinity Capture-Western
ASH2LMEF2D11452818026121 Affinity Capture-Western
PRKACAMEF2D11037318299387 Biochemical Activity
PRKACAMEF2D11155318299387 Biochemical Activity
SNCAMEF2D11037318541383 Reconstituted Complex
SNCAMEF2D11250618541383 Reconstituted Complex
PRMT5MEF2D11037319188441 Reconstituted Complex
PRMT5MEF2D11568819188441 Reconstituted Complex
CARM1MEF2D11037319188441 Reconstituted Complex
CARM1MEF2D11576019188441 Reconstituted Complex
COPS5MEF2D11037320936779 Two-hybrid
COPS5MEF2D11618320936779 Two-hybrid
HIRAMEF2D11037321414300 Affinity Capture-Western
HIRAMEF2D11314121414300 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99533
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-164'