AutismKB 2.0

Annotation Details for MEIS2


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Basic Information Top
Gene Symbol:MEIS2 ( HsT18361,MGC2820,MRG1 )
Gene Full Name: Meis homeobox 2
Band: 15q14
Quick LinksEntrez ID:4212; OMIM: 601740; Uniprot ID:MEIS2_HUMAN; ENSEMBL ID: ENSG00000134138; HGNC ID: 7001
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding10764806
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding10764806
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding10764806
GO:0003712ISS-transcription cofactor activity-
GO:0003714TAS-transcription corepressor activity10764806
GO:0005515IPI-protein binding22458338
GO:0008134ISS-transcription factor binding-
GO ID Evidence Qualifier GO_term References
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter10764806
GO:0001654IEA-eye development-
GO:0006366TAS-transcription from RNA polymerase II promoter10764806
GO:0008542IEA-visual learning-
GO:0009612IEA-response to mechanical stimulus-
GO:0031016IEA-pancreas development-
GO:0045638ISS-negative regulation of myeloid cell differentiation-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter10764806
GO:0070848IEA-response to growth factor-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PBX1MEIS211037620211142 Two-hybrid
PBX1MEIS211112020211142 Two-hybrid
TRIM25MEIS211037620211142 Two-hybrid
TRIM25MEIS211350020211142 Two-hybrid
ZNHIT3MEIS211037620211142 Two-hybrid
ZNHIT3MEIS211473620211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108564
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000210-23'