AutismKB 2.0

Annotation Details for RAB8A


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Basic Information Top
Gene Symbol:RAB8A ( MEL,RAB8 )
Gene Full Name: RAB8A, member RAS oncogene family
Band: 19p13.11
Quick LinksEntrez ID:4218; OMIM: 165040; Uniprot ID:RAB8A_HUMAN; ENSEMBL ID: ENSG00000167461; HGNC ID: 7007
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139TAS-Golgi membrane-
GO:0005813IDA-centrosome24421332
GO:0005814IEA-centriole-
GO:0005829TAS-cytosol-
GO:0005886IBA-plasma membrane-
GO:0005929IDA-cilium17646400
GO:0005929IDAcolocalizes_withcilium21844891
GO:0008021IBA-synaptic vesicle-
GO:0014069IEA-postsynaptic density-
GO:0030140IEA-trans-Golgi network transport vesicle-
GO:0030670IEA-phagocytic vesicle membrane-
GO:0031012IDA-extracellular matrix23979707
GO:0032588TAS-trans-Golgi network membrane-
GO:0036064IEA-ciliary basal body-
GO:0043025IEA-neuronal cell body-
GO:0043197IEA-dendritic spine-
GO:0045335IDA-phagocytic vesicle21255211
GO:0055038IDA-recycling endosome membrane19864458
GO:0055038TAS-recycling endosome membrane-
GO:0070062IDA-extracellular exosome19056867
GO:0097546IEA-ciliary base-
GO:0097730IDA-non-motile cilium17574030
GO ID Evidence Qualifier GO_term References
GO:0003924IDA-GTPase activity17646400
GO:0005515IPI-protein binding15837803
GO:0005525IDA-GTP binding20937701
GO:0017137ISS-Rab GTPase binding-
GO:0019003IDA-GDP binding20937701
GO:0019901IEA-protein kinase binding-
GO:0031489IPI-myosin V binding24006491
GO ID Evidence Qualifier GO_term References
GO:0000086TAS-G2/M transition of mitotic cell cycle-
GO:0006904IDA-vesicle docking involved in exocytosis17574030
GO:0006914IEA-autophagy-
GO:0007409ISS-axonogenesis-
GO:0009306IBA-protein secretion-
GO:0010506IMP-regulation of autophagy27103069
GO:0032869ISS-cellular response to insulin stimulus-
GO:0043687TAS-post-translational protein modification-
GO:0048169IEA-regulation of long-term neuronal synaptic plasticity-
GO:0048210IDA-Golgi vesicle fusion to target membrane17574030
GO:0051223IEA-regulation of protein transport-
GO:0060271IDA-cilium assembly17574030
GO:0060271IMP-cilium assembly17646400
GO:0061024TAS-membrane organization-
GO:0072659IBA-protein localization to plasma membrane-
GO:0072659ISS-protein localization to plasma membrane-
GO:0097711TAS-ciliary basal body docking-
GO:0098969IEA-neurotransmitter receptor transport to postsynaptic membrane-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAB8AGDI211038210512627 Reconstituted Complex
RAB8AGDI210893310512627 Reconstituted Complex
MAP4K2RAB8A1103828643544 Affinity Capture-Western; Co-fractionation; Two-hybrid
MAP4K2RAB8A1118098643544 Affinity Capture-Western; Co-fractionation; Two-hybrid
OPTNRAB8A11038211137014 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
OPTNRAB8A11543611137014 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL4RAB8A11038211773082 12176990 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL4RAB8A12512011773082 12176990 12590134 Affinity Capture-Western; Reconstituted Complex
RPH3ARAB8A11038212578829 Affinity Capture-Western
RPH3ARAB8A11656012578829 Affinity Capture-Western
RPH3ALRAB8A11038212578829 Affinity Capture-Western
RPH3ALRAB8A11488012578829 Affinity Capture-Western
RIMS2RAB8A11038212578829 Affinity Capture-Western
RIMS2RAB8A11505112578829 Affinity Capture-Western
BAT3RAB8A11038216169070 Two-hybrid
BAT3RAB8A11364716169070 Two-hybrid
RAB10RAB8A11038217353931 Affinity Capture-MS
RAB10RAB8A11609617353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96960
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070424-36'