Annotation Details for MLLT1
Basic Information Top
| Gene Symbol: | MLLT1 ( ENL,LTG19,YEATS1 ) |
|---|---|
| Gene Full Name: | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| Band: | 19p13.3 |
| Quick Links | Entrez ID:4298; OMIM: 159556; Uniprot ID:ENL_HUMAN; ENSEMBL ID: ENSG00000130382; HGNC ID: 7134 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001650 | IDA | - | fibrillar center | - |
| GO:0005634 | TAS | - | nucleus | 8080983 |
| GO:0005654 | IDA | - | nucleoplasm | - |
| GO:0005654 | TAS | - | nucleoplasm | - |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0008023 | IDA | - | transcription elongation factor complex | 22195968 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003677 | TAS | - | DNA binding | 7991593 |
| GO:0005515 | IPI | - | protein binding | 20153263 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006355 | IEA | - | regulation of transcription, DNA-templated | - |
| GO:0006366 | TAS | - | transcription from RNA polymerase II promoter | - |
| GO:0006368 | TAS | - | transcription elongation from RNA polymerase II promoter | - |
| GO:0006469 | IEA | - | negative regulation of protein kinase activity | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| MLLT1 | CDK9 | 110444 | 19956800 | Affinity Capture-Western |
| MLLT1 | CDK9 | 107459 | 19956800 | Affinity Capture-Western |
| CBX8 | MLLT1 | 110444 | 11313972 | Affinity Capture-Western; Two-hybrid |
| CBX8 | MLLT1 | 121487 | 11313972 | Affinity Capture-Western; Two-hybrid |
| WDR5 | MLLT1 | 110444 | 18829457 18829459 | Co-crystal Structure; Reconstituted Complex |
| WDR5 | MLLT1 | 116272 | 18829457 18829459 | Co-crystal Structure; Reconstituted Complex |
| AFF1 | MLLT1 | 110444 | 19956800 | Two-hybrid |
| AFF1 | MLLT1 | 110445 | 19956800 | Two-hybrid |
| No data |
| No data |
- MGI ID: MGI:1927238
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-081105-45



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