AutismKB 2.0

Annotation Details for ACHE


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Basic Information Top
Gene Symbol:ACHE ( ARACHE,N-ACHE,YT )
Gene Full Name: acetylcholinesterase
Band: 7q22.1
Quick LinksEntrez ID:43; OMIM: 100740; Uniprot ID:ACES_HUMAN; ENSEMBL ID: ENSG00000087085; HGNC ID: 108
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IDA-extracellular region1517212
GO:0005576TAS-extracellular region11283752
GO:0005605NAS-basal lamina16289501
GO:0005615IEA-extracellular space-
GO:0005634IEA-nucleus-
GO:0005794IDA-Golgi apparatus15454088
GO:0005886TAS-plasma membrane-
GO:0009986IEA-cell surface-
GO:0016020IDA-membrane16262697
GO:0030054IEA-cell junction-
GO:0031225IEA-anchored component of membrane-
GO:0031594IEA-neuromuscular junction-
GO:0043083IEA-synaptic cleft-
GO:0045202IDA-synapse8460160
GO:0048471IDA-perinuclear region of cytoplasm14766237
GO ID Evidence Qualifier GO_term References
GO:0001540TAS-amyloid-beta binding11283752
GO:0003990IDA-acetylcholinesterase activity1517212
GO:0003990IMP-acetylcholinesterase activity1517212
GO:0003990TAS-acetylcholinesterase activity-
GO:0004104IDA-cholinesterase activity1517212
GO:0005515IPI-protein binding10800960
GO:0005518IDA-collagen binding12524166
GO:0016787IDA-hydrolase activity1517212
GO:0017171IDA-serine hydrolase activity3954986
GO:0042166IDA-acetylcholine binding8349597
GO:0042166NAS-acetylcholine binding1517212
GO:0042803IPI-protein homodimerization activity12524166
GO:0042803NAS-protein homodimerization activity1517212
GO:0043236IDA-laminin binding12524166
GO:0043621IEA-protein self-association-
GO ID Evidence Qualifier GO_term References
GO:0001507NAS-acetylcholine catabolic process in synaptic cleft1517212
GO:0001919IEA-regulation of receptor recycling-
GO:0002076IEP-osteoblast development15454088
GO:0006260TAS-DNA replication11283752
GO:0006581IDA-acetylcholine catabolic process1517212
GO:0006656TAS-phosphatidylcholine biosynthetic process-
GO:0007155IDA-cell adhesion15454088
GO:0007155TAS-cell adhesion11283752
GO:0007399TAS-nervous system development11283752
GO:0007416TAS-synapse assembly11283752
GO:0007517TAS-muscle organ development11283752
GO:0008283TAS-cell proliferation11283752
GO:0009611TAS-response to wounding11283752
GO:0031623IEA-receptor internalization-
GO:0032223IC-negative regulation of synaptic transmission, cholinergic1517212
GO:0042136TAS-neurotransmitter biosynthetic process-
GO:0042982TAS-amyloid precursor protein metabolic process12769797
GO:0045212IEA-neurotransmitter receptor biosynthetic process-
GO:0050714TAS-positive regulation of protein secretion11283752
GO:0051262IEA-protein tetramerization-
GO:0060041IEA-retina development in camera-type eye-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
APPACHE10656112427014 Reconstituted Complex
APPACHE10684812427014 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ACHErs12705094, rs1799806, rs2571598, rs3087504, rs3757869 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:87876
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010906-1'