AutismKB 2.0

Annotation Details for MMP8


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Basic Information Top
Gene Symbol:MMP8 ( CLG1,HNC,MMP-8,PMNL-CL )
Gene Full Name: matrix metallopeptidase 8 (neutrophil collagenase)
Band: 11q22.2
Quick LinksEntrez ID:4317; OMIM: 120355; Uniprot ID:MMP8_HUMAN; ENSEMBL ID: ENSG00000118113; HGNC ID: 7175
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005615IDA-extracellular space2164002
GO:0035580TAS-specific granule lumen-
GO:1904724TAS-tertiary granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0004222TAS-metalloendopeptidase activity-
GO:0004252IDA-serine-type endopeptidase activity2164002
GO:0004252TAS-serine-type endopeptidase activity-
GO:0008270TAS-zinc ion binding2164002
GO ID Evidence Qualifier GO_term References
GO:0006508IDA-proteolysis2164002
GO:0022617TAS-extracellular matrix disassembly-
GO:0030574TAS-collagen catabolic process-
GO:0035987IEP-endodermal cell differentiation23154389
GO:0043312TAS-neutrophil degranulation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BCANMMP812196410986281 Biochemical Activity
BCANMMP811046010986281 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1202395
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018