AutismKB 2.0

Annotation Details for MPO


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Basic Information Top
Gene Symbol:MPO ( - )
Gene Full Name: myeloperoxidase
Band: 17q22
Quick LinksEntrez ID:4353; OMIM: 606989; Uniprot ID:PERM_HUMAN; ENSEMBL ID: ENSG00000005381; HGNC ID: 7218
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space10772654
GO:0005634IDA-nucleus21630459
GO:0005739IEA-mitochondrion-
GO:0005764TAS-lysosome8621627
GO:0030141IDA-secretory granule11907569
GO:0035578TAS-azurophil granule lumen-
GO:0042582IDA-azurophil granule2981589
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003682TAS-chromatin binding2829220
GO:0004601IDA-peroxidase activity10772654
GO:0008201IDA-heparin binding11907569
GO:0020037IEA-heme binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001878IEA-response to yeast-
GO:0002149IEA-hypochlorous acid biosynthetic process-
GO:0002679IEA-respiratory burst involved in defense response-
GO:0006952TAS-defense response8621627
GO:0006979TAS-response to oxidative stress2903767
GO:0007568IEA-aging-
GO:0009612IEA-response to mechanical stimulus-
GO:0019430IEA-removal of superoxide radicals-
GO:0032094IEA-response to food-
GO:0032496IEA-response to lipopolysaccharide-
GO:0034374IDA-low-density lipoprotein particle remodeling10772654
GO:0042742IBA-defense response to bacterium-
GO:0042744IDA-hydrogen peroxide catabolic process10772654
GO:0043066TAS-negative regulation of apoptotic process10801811
GO:0043312TAS-neutrophil degranulation-
GO:0044130IEA-negative regulation of growth of symbiont in host-
GO:0050832IEA-defense response to fungus-
GO:0055114IDA-oxidation-reduction process10772654
GO:1990268IEA-response to gold nanoparticle-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
MPOrs2333227 Gene overview in AlzGene
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Animal Model Top
  • MGI ID: MGI:97137
  • Data Attributes: MGI curated and HomoloGene calculated
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018