AutismKB 2.0

Annotation Details for MYO1B


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Basic Information Top
Gene Symbol:MYO1B ( myr1 )
Gene Full Name: myosin IB
Band: 2q32.3
Quick LinksEntrez ID:4430; OMIM: 606537; Uniprot ID:MYO1B_HUMAN; ENSEMBL ID: ENSG00000128641; HGNC ID: 7596
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737ISS-cytoplasm-
GO:0005769IDA-early endosome16219689
GO:0005884IDA-actin filament16219689
GO:0005886IDA-plasma membrane-
GO:0005886ISS-plasma membrane-
GO:0005903ISS-brush border-
GO:0010008IDA-endosome membrane16219689
GO:0016459IEA-myosin complex-
GO:0030175ISS-filopodium-
GO:0032588IDAcolocalizes_withtrans-Golgi network membrane21666684
GO:0045177IEA-apical part of cell-
GO:0048471IDA-perinuclear region of cytoplasm21666684
GO:0070062IDA-extracellular exosome19056867
GO:0071944ISS-cell periphery-
GO ID Evidence Qualifier GO_term References
GO:0000146IMP-microfilament motor activity21666684
GO:0000146ISS-microfilament motor activity-
GO:0005516IEA-calmodulin binding-
GO:0005524IMP-ATP binding21666684
GO:0005524ISS-ATP binding-
GO:0005546ISS-phosphatidylinositol-4,5-bisphosphate binding-
GO:0005547ISS-phosphatidylinositol-3,4,5-trisphosphate binding-
GO:0030898IEA-actin-dependent ATPase activity-
GO:0045296IDA-cadherin binding25468996
GO:0051015IMP-actin filament binding21666684
GO ID Evidence Qualifier GO_term References
GO:0006892IMP-post-Golgi vesicle-mediated transport21666684
GO:0007015IMP-actin filament organization21666684
GO:0030048ISS-actin filament-based movement-
GO:0051017ISS-actin filament bundle assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MYO1BEIF4A211056717353931 Affinity Capture-MS
MYO1BEIF4A210829017353931 Affinity Capture-MS
MYCMYO1B11069417353931 Affinity Capture-MS
MYCMYO1B11056717353931 Affinity Capture-MS
BRF2MYO1B12057817353931 Affinity Capture-MS
BRF2MYO1B11056717353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107752
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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