AutismKB 2.0

Annotation Details for MSH3


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Basic Information Top
Gene Symbol:MSH3 ( DUP,MGC163306,MGC163308,MRP1 )
Gene Full Name: mutS homolog 3 (E. coli)
Band: 5q14.1
Quick LinksEntrez ID:4437; OMIM: 600887; Uniprot ID:MSH3_HUMAN; ENSEMBL ID: ENSG00000113318; HGNC ID: 7326
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0016020IDA-membrane19946888
GO:0032302IDA-MutSbeta complex8942985
GO ID Evidence Qualifier GO_term References
GO:0003697IDAcontributes_tosingle-stranded DNA binding11809883
GO:0005515IPI-protein binding8942985
GO:0005524IEA-ATP binding-
GO:0019899IPI-enzyme binding11427529
GO:0030983IDAcontributes_tomismatched DNA binding8942985
GO:0032137IDANOTguanine/thymine mispair binding11809883
GO:0032139IDAcontributes_todinucleotide insertion or deletion binding8942985
GO:0032142IDAcontributes_tosingle guanine insertion binding8942985
GO:0032181IDAcontributes_todinucleotide repeat insertion binding8942985
GO:0032357IDANOT contributes_tooxidized purine DNA binding11756455
GO:0042803IDANOTprotein homodimerization activity8942985
GO ID Evidence Qualifier GO_term References
GO:0006281IDA-DNA repair8942985
GO:0006298IMP-mismatch repair8782829
GO:0006298TAS-mismatch repair-
GO:0043570IMP-maintenance of DNA repeat elements16388310
GO:0045910IDA-negative regulation of DNA recombination17715146
GO:0051096IDA-positive regulation of helicase activity17715146
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MSH3BARD110705611498787 Reconstituted Complex
MSH3BARD111057411498787 Reconstituted Complex
MSH3BRCA110714011498787 14578343 Protein-peptide; Reconstituted Complex
MSH3BRCA111057411498787 14578343 Protein-peptide; Reconstituted Complex
MSH3MLH111043817148452 Affinity Capture-MS
MSH3MLH111057417148452 Affinity Capture-MS
MSH3MSH21105738942985 9774676 10029069 14657349 Affinity Capture-MS; Reconstituted Complex
MSH3MSH21105748942985 9774676 10029069 14657349 Affinity Capture-MS; Reconstituted Complex
PCNAMSH311114211005803 11274057 12171929 Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptide
PCNAMSH311057411005803 11274057 12171929 Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptide
EXO1MSH311460211427529 Reconstituted Complex
EXO1MSH311057411427529 Reconstituted Complex
PMS2MSH311140417148452 Affinity Capture-MS
PMS2MSH311057417148452 Affinity Capture-MS
RPA4MSH311897519468048 Reconstituted Complex
RPA4MSH311057419468048 Reconstituted Complex
XPAMSH311334419468048 Reconstituted Complex
XPAMSH311057419468048 Reconstituted Complex
SLX4MSH312409719596235 Affinity Capture-MS
SLX4MSH311057419596235 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109519
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060526-307'