AutismKB 2.0

Annotation Details for MSN


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Basic Information Top
Gene Symbol:MSN ( - )
Gene Full Name: moesin
Band: Xq12
Quick LinksEntrez ID:4478; OMIM: 309845; Uniprot ID:MOES_HUMAN; ENSEMBL ID: ENSG00000147065; HGNC ID: 7373
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001931IEA-uropod-
GO:0005615IDA-extracellular space16502470
GO:0005634IDA-nucleus16791210
GO:0005737IDA-cytoplasm16791210
GO:0005829IDA-cytosol-
GO:0005856TAS-cytoskeleton16130169
GO:0005886IDA-plasma membrane-
GO:0005902IDA-microvillus12082081
GO:0005925IDA-focal adhesion21423176
GO:0005925IDAcolocalizes_withfocal adhesion21282464
GO:0009986IDA-cell surface15922359
GO:0016323IEA-basolateral plasma membrane-
GO:0016324IDA-apical plasma membrane24862762
GO:0030175IDA-filopodium12082081
GO:0031143IDA-pseudopodium24065547
GO:0031528IEA-microvillus membrane-
GO:0031982IDA-vesicle19190083
GO:0043209IEA-myelin sheath-
GO:0045177IDA-apical part of cell12082081
GO:0048471IDA-perinuclear region of cytoplasm24862762
GO:0070062IDA-extracellular exosome12519789
GO:0071944IDA-cell periphery22291017
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0003725IDA-double-stranded RNA binding21266579
GO:0003779IEA-actin binding-
GO:0005102IPI-receptor binding15819698
GO:0005200TAS-structural constituent of cytoskeleton1924289
GO:0005515IPI-protein binding7844168
GO:0019899IPI-enzyme binding15922359
GO:0019901IPI-protein kinase binding19255442
GO:0050839IPI-cell adhesion molecule binding12082081
GO ID Evidence Qualifier GO_term References
GO:0001771IDA-immunological synapse formation27405666
GO:0006928TAS-movement of cell or subcellular component16130169
GO:0007010IEA-cytoskeleton organization-
GO:0007159IEP-leukocyte cell-cell adhesion12082081
GO:0008360IMP-regulation of cell shape24862762
GO:0008361IMP-regulation of cell size24862762
GO:0008361IMPNOTregulation of cell size22467863
GO:0010628IGI-positive regulation of gene expression23264465
GO:0022612IMP-gland morphogenesis24862762
GO:0022614IEP-membrane to membrane docking12082081
GO:0042098IDA-T cell proliferation27405666
GO:0045198IMP-establishment of epithelial cell apical/basal polarity24862762
GO:0050900IEP-leukocyte migration12082081
GO:0061028IGI-establishment of endothelial barrier23264465
GO:0070489IDA-T cell aggregation27405666
GO:0071394IDA-cellular response to testosterone stimulus24065547
GO:0071803IEA-positive regulation of podosome assembly-
GO:0072678IDA-T cell migration27405666
GO:1902115IGI-regulation of organelle assembly21148287
GO:1902966IGI-positive regulation of protein localization to early endosome21148287
GO:1903364IGI-positive regulation of cellular protein catabolic process21148287
GO:2000401IMP-regulation of lymphocyte migration19255442
GO:2000643IGI-positive regulation of early endosome to late endosome transport21148287
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MSNFAS10685115659383 Co-purification
MSNFAS11058415659383 Co-purification
MSNFASLG10685215659383 Co-purification
MSNFASLG11058415659383 Co-purification
MSNRHOA10688015659383 Co-purification
MSNRHOA11058415659383 Co-purification
MSNARHGDIA10688915659383 Co-purification
MSNARHGDIA11058415659383 Co-purification
MSNBID10710615659383 Co-purification
MSNBID11058415659383 Co-purification
MSNCASP810729115659383 Co-purification
MSNCASP811058415659383 Co-purification
MSNCASP1011058415659383 Co-purification
MSNCASP1010729315659383 Co-purification
MSNCD441073989472040 Reconstituted Complex
MSNCD441105849472040 Reconstituted Complex
MSNHLA-B11058417353931 Affinity Capture-MS
MSNHLA-B10935117353931 Affinity Capture-MS
MSNICAM21105849472040 Reconstituted Complex
MSNICAM21096119472040 Reconstituted Complex
MSNICAM31105849298994 11784723 Affinity Capture-Western; Reconstituted Complex
MSNICAM31096129298994 11784723 Affinity Capture-Western; Reconstituted Complex
MSNCD461103467884872 Affinity Capture-Western
MSNCD461105847884872 Affinity Capture-Western
EZRMSN1105847579708 8248180 15659383 Affinity Capture-Western; Co-purification; Reconstituted Complex
EZRMSN1132717579708 8248180 15659383 Affinity Capture-Western; Co-purification; Reconstituted Complex
SLC9A3R1MSN1147699430655 Reconstituted Complex
SLC9A3R1MSN1105849430655 Reconstituted Complex
SPNMSN1125719472040 9616160 Affinity Capture-Western; Reconstituted Complex
SPNMSN1105849472040 9616160 Affinity Capture-Western; Reconstituted Complex
MSNMSN11058410847681 Co-crystal Structure
SPTAN1MSN11258711441066 Affinity Capture-Western
SPTAN1MSN11058411441066 Affinity Capture-Western
SELLMSN11230211706008 Reconstituted Complex
SELLMSN11058411706008 Reconstituted Complex
NCF4MSN11076911716484 Affinity Capture-Western; Reconstituted Complex
NCF4MSN11058411716484 Affinity Capture-Western; Reconstituted Complex
NCF1MSN57572411716484 Affinity Capture-Western; Reconstituted Complex
NCF1MSN11058411716484 Affinity Capture-Western; Reconstituted Complex
VCAM1MSN11325512082081 Affinity Capture-Western; Reconstituted Complex
VCAM1MSN11058412082081 Affinity Capture-Western; Reconstituted Complex
SELPLGMSN11230412115638 Reconstituted Complex
SELPLGMSN11058412115638 Reconstituted Complex
TSC1MSN11309912226091 Two-hybrid
TSC1MSN11058412226091 Two-hybrid
MAPK8MSN11158515659383 Co-purification
MAPK8MSN11058415659383 Co-purification
TNFRSF1AMSN11298615659383 Co-purification
TNFRSF1AMSN11058415659383 Co-purification
FADDMSN11430215659383 Co-purification
FADDMSN11058415659383 Co-purification
TNFRSF10BMSN11432315659383 Co-purification
TNFRSF10BMSN11058415659383 Co-purification
Gene Symbol Interactant Interaction ID References Description
TSC1MSN2485410806479 Hamartin interacts with moesin. This interaction was modeled on a demonstrated interaction between murine hamartin and human moesin.
SYKMSN15110912387735 Syk interacts with moesin. This interaction was modeled on a demonstrated interaction between Syk and moesin from unspecified species.
SLC9A3R1MSN548559430655 moesin interacts with hNHE-RF.
CD93MSN26203515819698 Moesin interacts with CD93.
Gene Symbol Interactant Interaction ID References Description
PLECMSN0318011441066 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97167
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021211-2'