AutismKB 2.0

Annotation Details for MSR1


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Basic Information Top
Gene Symbol:MSR1 ( CD204,SCARA1,SR-A,phSR1,phSR2 )
Gene Full Name: macrophage scavenger receptor 1
Band: 8p22
Quick LinksEntrez ID:4481; OMIM: 153622; Uniprot ID:MSRE_HUMAN; ENSEMBL ID: ENSG00000038945; HGNC ID: 7376
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005581IEA-collagen trimer-
GO:0005829IEA-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane8093617
GO:0030666TAS-endocytic vesicle membrane-
GO:0034362IEA-low-density lipoprotein particle-
GO ID Evidence Qualifier GO_term References
GO:0005044IEA-scavenger receptor activity-
GO:0005515IPI-protein binding17237231
GO:0030169ISS-low-density lipoprotein particle binding12376530
GO ID Evidence Qualifier GO_term References
GO:0006898TAS-receptor-mediated endocytosis-
GO:0010744ISS-positive regulation of macrophage derived foam cell differentiation12376530
GO:0010886ISS-positive regulation of cholesterol storage-
GO:0030301ISS-cholesterol transport12376530
GO:0034381ISS-plasma lipoprotein particle clearance12376530
GO:0042953IEA-lipoprotein transport-
GO:0071407IEA-cellular response to organic cyclic compound-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MSR1HSPA1A10953511785981 Affinity Capture-Western; Reconstituted Complex
MSR1HSPA1A11058711785981 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98257
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018